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Creators: Chahl, Loris A.
Date: 2012
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.13/1309127
Description: Schizophrenia is a debilitating psychiatric disorder. The limitations of current treatments for schizophrenia have led to an ongoing search for new drug targets. The observations that subjects with sc... More
Date: 2011
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/936563
Description: The effects of subchronic subcutaneous treatment with tachykinin receptor antagonists over nine days on the repeated mild stress response induced by daily subcutaneous injections and on the severe acu... More
Reviewed: Reviewed
Creators: Chahl, Loris A.
Date: 2011
Language: eng
Resource Type: book chapter
Identifier: http://hdl.handle.net/1959.13/1325166
Description: Depression and schizophrenia are major psychiatric disorders that cause much human suffering. Current treatments have major limitations and new drug targets are eagerly sought. Study of transient rece... More
Date: 2010
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/930736
Description: Capsaicin, the hot chemical in chillies, administered to neonatal rats, causes destruction of polymodal nociceptive primary afferent neurons by acting on TRPV1 receptors causing intrinsic somatosensor... More
Reviewed: Reviewed
Creators: Chahl, Loris A.
Date: 2006
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/26895
Description: The classical tachykinins, substance P, neurokinin A and neurokinin B are predominantly found in the nervous system where they act as neurotransmitters and neuromodulators. Their respective preferred ... More
Reviewed: Reviewed
Date: 2005
Resource Type: journal article
Identifier: uon:1597
Description: 1. Schizophrenia is considered to be a neurodevelopmental disorder with origins in the prenatal or neonatal period. Brains from subjects with schizophrenia have enlarged ventricles, reduced cortical t... More
Reviewed: Reviewed
Date: 2001
Resource Type: journal article
Identifier: uon:1083
Description: Background: Changes in levels of substance P and substance P-binding sites have been implicated in schizophrenia. However, no studies have used receptor-specific antibodies to directly investigate the... More
Reviewed: Reviewed
Date: 2001
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/26743
Description: In this study the localizations of tachykinin neurokinin-1 (NK1) and neurokinin-3 (NK3) receptors in the guinea-pig brain are described. In agreement with studies in rat and human brain, the neurons t... More
Reviewed: Reviewed
Date: 2000
Resource Type: journal article
Identifier: uon:2883
Description: The distribution of tachykinin NK₁ and NK₃ receptors in the prefrontal (Brodmann area 9) and visual cortex (Brodmann area 17) of formalin-fixed postmortem human brain tissue was studied by immunohisto... More
Reviewed: Reviewed
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