GlobalView

Showing items 1 - 15 of 243.

Add to Quick Collection   All 243 Results

Sort:
 Add All Items to Quick Collection
Creators: Gorski, Mathias | van der Most, Peter J. | Li, Yong | Sedaghat, S | Smith, AV | Sorice, R | Stengel, B | Stracke, S | Strauch, K | Toniolo, D | Uitterlinden, AG | Ulivi, S | Viikari, JS | Tayo, Bamidele | Voelker, U | Vollenweider, P | Voelzke, H | Vuckovic, D | Waldenberger, M | Wang, JJ | Yang, Q | Chasman, DI | Tromp, G | Snieder, H | Tin, Adrienne | Heid, IM | Fox, CS | Koettgen, A | Pattaro, C | Boeger, CA | Fuchsberger, C | Feitosa, Mary F. | Aspelund, Thor | Attia, John | Biffar, Reiner | Bochud, Murielle | Boerwinkle, Eric | Borecki, Ingrid | Teumer, Alexander | Bottinger, Erwin P. | Chen, Ming-Huei | Chouraki, Vincent | Ciullo, Marina | Coresh, Josef | Cornelis, Marilyn C. | Curhan, Gary C. | d'Adamo, Adamo P. | Dehghan, Abbas | Dengler, Laura | Chu, Audrey Y. | Ding, Jingzhong | Eiriksdottir, Gudny | Endlich, K | Enroth, S | Esko, T | Franco, OH | Gasparini, P | Gieger, C | Girotto, G | Gottesman, O | Li, Man | Gudnason, V | Gyllensten, U | Hancock, Stephen J. | Harris, TB | Helmer, C | Hoellerer, S | Hofer, E | Hofman, A | Holliday, Elizabeth | Homuth, G | Mijatovic, Vladan | Hu, FB | Huth, C | Hutri-Kahonen, N | Hwang, S-J | Imboden, M | Johansson, A | Kahonen, M | Koenig, W | Kraemer, H | Kramer, BK | Nolte, Ilja M. | Kumar, A | Kutalik, Z | Lambert, J-C | Launer, LJ | Lehtimaki, T | de Borst, M | Navis, G | Swertz, M | Liu, Y | Lohman, K | Cocca, Massimiliano | Loos, RJF | Lu, Y | Lyytikainen, L-P | McEvoy, Mark A. | Meisinger, C | Meitinger, T | Metspalu, A | Metzger, M | Mihailov, E | Mitchell, P | Taliun, Daniel | Nauck, M | Oldehinkel, AJ | Olden, M | Penninx, BWJH | Pistis, G | Pramstaller, PP | Probst-Hensch, N | Raitakari, OT | Rettig, R | Ridker, PM | Gomez, Felicia | Rivadeneira, F | Robino, A | Rosas, SE | Ruderfer, D | Ruggiero, D | Saba, Y | Sala, C | Schmidt, H | Schmidt, R | Scott, Rodney J.
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1352081
Description: HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete refe... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Creators: de Vries, Paul S. | Sabater-Lleal, Maria | Marioni, Riccardo E. | Steri, Maristella | Weng, Lu-Chen | Pool, Rene | Grossmann, Vera | Brody, Jennifer A. | Venturini, Cristina | Tanaka, Toshiko | Rose, Lynda M. | Oldmeadow, Christopher | Chasman, Daniel I. | Mazur, Johanna | Basu, Saonli | Frånberg, Mattias | Yang, Qiong | Ligthart, Symen | Hottenga, Jouke J. | Rumley, Ann | Mulas, Antonella | de Craen, Anton J. M. | Grotevendt, Anne | Trompet, Stella | Taylor, Kent D. | Delgado, Graciela E. | Kifley, Annette | Lopez, Lorna M. | Berentzen, Tina L. | Mangino, Massimo | Bandinelli, Stefania | Morrison, Alanna C. | Hamsten, Anders | Tofler, Geoffrey | Ahluwalia, Tarunveer S. | de Maat, Moniek P. M. | Draisma, Harmen H. M. | Lowe, Gordon D. | Zoledziewska, Magdalena | Sattar, Naveed | Lackner, Karl J. | Völker, Uwe | McKnight, Barbara | Huang, Jie | Holliday, Elizabeth G. | Teumer, Alexander | McEvoy, Mark A. | Starr, John M. | Hysi, Pirro G. | Hernandez, Dena G. | Guan, Weihua | Rivadeneira, Fernando | McArdle, Wendy L. | Slagboom, P. Eline | Zeller, Tanja | Psaty, Bruce M. | Kleber, Marcus E. | Uitterlinden, André G. | de Geus, Eco J. C. | Stott, David J. | Binder, Harald | Hofman, Albert | Franco, Oscar H. | Rotter, Jerome I. | Ferrucci, Luigi | Spector, Tim D. | Deary, Ian J. | Chen, Ming-Huei | März, Winfried | Greinacher, Andreas | Wild, Philipp S. | Cucca, Francesco | Boomsma, Dorret I. | Watkins, Hugh | Tang, Weihong | Ridker, Paul M. | Jukema, Jan W. | Scott, Rodney J. | Wang, Jie Jin | Mitchell, Paul | Hansen, Torben | O'Donnell, Christopher J. | Smith, Nicholas L. | Strachan, David P. | Dehghan, Abbas | Attia, John R.
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1350669
Description: An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputatio... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1353559
Description: Plasma cell disorders (PCD) range from benign to highly malignant disease. The ability to detect risk-stratifying aberrations based on cytogenetic and molecular genetic assays plays an increasing role... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1332081
Description: A dysfunctional endometrial renin–angiotensin system (RAS) could aid the growth and spread of endometrial cancer. To determine if the RAS is altered in endometrial cancer, we measured RAS gene express... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1352825
Description: Placental CRH production increases with advancing pregnancy in women and its course predicts gestational length. We hypothesized that CRH gene expression in the placenta is epigenetically controlled s... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2017
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1350586
Description: Germline variants within BRCA1 or BRCA2 genes account for approximately 25% of familial aggregations of breast-ovarian cancers. Low or no expression of BRCA1 in breast and ovarian cancers is associate... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1348843
Description: A recent meta-analysis of multiple genome-wide association and follow-up endometrial cancer case-control datasets identified a novel genetic risk locus for this disease at chromosome 14q32.33. To prio... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1315939
Description: Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromoso... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1348637
Description: Background: The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers, but its mechanism of action remains unknown. In a genome-wide search for tandem repea... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1331062
Description: Due to the lack of high-throughput genetic assays for tandem repeats, there is a paucity of knowledge about the role they may play in disease. A polymorphic CA repeat in the promoter region of the ins... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1316051
Description: Paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) is the most common cancer of childhood, yet little is known about BCP-ALL predisposition. In this study, in 2,187 cases of European ... More
Reviewed: Reviewed
Date: 2016
Keyword: MTHFR | homocysteine | cataract
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1346812
Description: Importance: Methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been shown to influence homocysteine levels; homocysteine has been implicated as a cataractogenic stressor. Objective: To inv... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1327827
Description: p53 is expressed as multiple smaller isoforms whose functions in cancer are not well understood. The p53 isoforms demonstrate abnormal expression in different cancers, suggesting they are important in... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1347704
Description: Measuring cell proliferation can be performed by a number of different methods, each with varying levels of sensitivity, reproducibility and compatibility with high-throughput formatting. This protoco... More
Reviewed: Reviewed
Date: 2016
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1347257
Description: Familial Adenomatous Polyposis (FAP) is the second most common inherited predisposition to colorectal cancer (CRC) associated with the development of hundreds to thousands of adenomas in the colon and... More
Full Text: Full Text
Reviewed: Reviewed
Image Thumbnail