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Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1334490
Description: Chlorpromazine is a phenothiazine-derived antipsychotic drug (APD) that inhibits clathrin-mediated endocytosis (CME) in cells by an unknown mechanism. We examined whether its action and that of other ... More
Reviewed: Reviewed
Date: 2015
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1333393
Description: The use of 3-dimensional (3D) collagen gels has yielded new insights into the migratory behaviour of cancer cells. While the large GTPase dynamin has emerged as an important regulator of cancer cell m... More
Reviewed: Reviewed
Date: 2015
Keyword: molecules | dynamin | skin | exocytosis
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1339614
Description: Hormones and neurotransmitters are stored in specialised vesicles and released from excitable cells through exocytosis. During vesicle fusion with the plasma membrane, a transient fusion pore is creat... More
Reviewed: Reviewed
Creators: Mhd Bakri, Yuhanis
Date: 2015
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/1295874
Description: Research Doctorate - Doctor of Philosophy (PhD)
Full Text: Full Text
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Date: 2014
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1304704
Description: Virtual screening of the ChemDiversity and ChemBridge compound databases against dynamin I (dynI) GTPase activity identified 2,5-bis-(benzylamino)-1,4- benzoquinone 1 as a 273 ± 106 µM inhibitor. In s... More
Reviewed: Reviewed
Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1300827
Description: Dynamin GTPase activity increases when it oligomerizes either into helices in the presence of lipid templates or into rings in the presence of SH3 domain proteins. Dynasore is a dynamin inhibitor of m... More
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Reviewed: Reviewed
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Date: 2013
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1300476
Description: Many pathogens hijack existing endocytic trafficking pathways to exert toxic effects in cells. Dynamin controls various steps of the intoxication process used by numerous pathogenic bacteria, viruses,... More
Reviewed: Reviewed
Date: 2012
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/935828
Description: Research Doctorate - Doctor of Philosophy (PhD)
Full Text: Full Text
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Date: 2012
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/1311689
Description: Mammalian spermatozoa must complete an acrosome reaction prior to fertilizing an oocyte. The acrosome reaction is a unique exocytotic event involving a series of prolonged membrane fusions that ultima... More
Reviewed: Reviewed
Creators: Holland, Ian P.
Date: 2011
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/927961
Description: Research Doctorate - Doctor of Philosophy (PhD)
Full Text: Full Text
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Date: 2004
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/33616
Description: We examined a number of ligands with the view of inhibiting the GTPase activity of dynamin. Dynamin contains a pleckstrin homology (PH) domain that interacts with lipids. We report a series of simple ... More
Reviewed: Reviewed
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