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Date: 2012
Language: eng
Resource Type: thesis
Identifier: http://hdl.handle.net/1959.13/935828
Description: Research Doctorate - Doctor of Philosophy (PhD)
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Date: 2011
Language: eng
Resource Type: conference paper
Identifier: http://hdl.handle.net/1959.13/1036310
Description: We show here that one of the 5-phosphatases, PIB5PA(phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A), is frequently down-regulated, or lost in metastatic melanomas, which is correlated with act... More
Date: 2009
Resource Type: journal article
Identifier: uon:8246
Description: Two azidobenzyl amide (4 and 23) and one 3-trifluoromethyl-3H-diazirin-3-ylphenyl (24) analogues of bis-tyrphostin (1, Bis-T) were synthesised as potential photoaffinity labels for the elucidation of ... More
Reviewed: Reviewed
Date: 2009
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/805717
Description: Chemotherapy, biological agents or combinations of both have had little impact on survival of patients with metastatic melanoma. Advances in understanding the genetic changes associated with the devel... More
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Reviewed: Reviewed
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Date: 2008
Language: eng
Resource Type: journal article
Identifier: http://hdl.handle.net/1959.13/42996
Description: Cantharidin (1) and its derivatives are of significant interest as serine/threonine protein phosphatase 1 and 2A inhibitors. Additionally, compounds of this type have displayed growth inhibition of va... More
Reviewed: Reviewed
Date: 2005
Language: eng
Resource Type: journal article
Identifier: uon:228
Description: Cotyledons of broad bean (Vicia faba L.) develop in an apoplasmic environment that shifts in composition from one dominated by hexoses to one dominated by sucrose. During the latter phase of developme... More
Reviewed: Reviewed
Date: 2003
Resource Type: journal article
Identifier: uon:3009
Description: There are a number of diseases where the 5-α-reductase (5AR) enzyme is of therapeutic interest as a drug target. Currently the crystal structure for 5-α-reductase is unavailable, thus ligand-based pha... More
Reviewed: Reviewed
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