https://novaprd-lb.newcastle.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 MRI Radiomic Signature of White Matter Hyperintensities Is Associated With Clinical Phenotypes https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48705 Wed 29 Mar 2023 17:38:49 AEDT ]]> Altered Cerebrospinal Fluid Clearance and Increased Intracranial Pressure in Rats 18 h After Experimental Cortical Ischaemia https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40200 Wed 29 Mar 2023 14:50:41 AEDT ]]> Decreased Intracranial Pressure Elevation and Cerebrospinal Fluid Outflow Resistance: A Potential Mechanism of Hypothermia Cerebroprotection Following Experimental Stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40646 Wed 29 Mar 2023 14:12:45 AEDT ]]> Prognostic accuracy and impact of cerebral collateral status on clinical and safety outcomes in acute ischemic stroke patients receiving reperfusion therapy: a systematic meta-analysis https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50288 Wed 28 Feb 2024 16:40:22 AEDT ]]> Prevalence and Impact of Cerebral Microbleeds on Clinical and Safety Outcomes in Acute Ischaemic Stroke Patients Receiving Reperfusion Therapy: A Systematic Review and Meta-Analysis https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53567 Wed 28 Feb 2024 16:32:39 AEDT ]]> Poor collateral flow with severe hypoperfusion explains worse outcome in acute stroke patients with atrial fibrillation https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52831 Wed 28 Feb 2024 16:31:25 AEDT ]]> Radiomics-Derived Brain Age Predicts Functional Outcome after Acute Ischemic Stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49987 Wed 28 Feb 2024 16:27:03 AEDT ]]> Pilot experience using a portable electrocardiography device for atrial fibrillation detection in an outpatient stroke clinic https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52719 Wed 28 Feb 2024 16:25:42 AEDT ]]> Psychological Stress Management and Stress Reduction Strategies for Stroke Survivors: A Scoping Review https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50112 Wed 28 Feb 2024 16:20:34 AEDT ]]> The Oxford Cognitive Screen for use with Australian people after stroke (OCS-AU): The adaptation process and determining cut scores for cognitive impairment using a cross-sectional normative study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50323 Wed 28 Feb 2024 16:19:08 AEDT ]]> Translation of nurse-initiated protocols to manage fever, hyperglycaemia and swallowing following stroke across Europe (QASC Europe): A pre-test/post-test implementation study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52943 Wed 28 Feb 2024 16:14:20 AEDT ]]> The Hunter-8 Scale Prehospital Triage Workflow for Identification of Large Vessel Occlusion and Brain Haemorrhage https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52878 Wed 28 Feb 2024 16:11:22 AEDT ]]> Clopidogrel Administration Impairs Post-Stroke Learning and Memory Recovery in Mice https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53239 Wed 28 Feb 2024 15:57:17 AEDT ]]> Association of Perfusion Lesion Variables With Functional Outcome in Patients With Mild Stroke and Large Vessel Occlusion Managed Medically https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51451 3 seconds on CTP. Regression analyses were used to identify clinical and imaging variables that predicted poor functional outcome. Results: A total of 139 patients with mild stroke were included, of whom 27 (19%) had poor functional outcome. Patients with poor outcome, compared with those with good outcome, had much larger perfusion lesion volume (median 80 mL vs 41 mL, p < 0.001). Perfusion lesion was a significant predictor of poor outcome in either univariable regression (crude OR = 1.02, 95% CI = [1.01-1.03]) or multivariable regression model (adjusted OR = 1.01, 95% CI = [1.01-1.02]), adjusting for occlusion site, good collaterals, baseline stroke severity, age, IV thrombolysis (IVT), and onset to scan time. A perfusion lesion of 65 mL was the optimal cutpoint to identify poor functional outcome (sensitivity = 59%, specificity = 77%). Patients with perfusion lesion ≥65 mL, compared with patients with perfusion lesion <65 mL, showed a much higher rate of poor functional outcome (38% vs 11%, p < 0.001). Of the 139 patients in this study, 95 received IVT. Patients treated with or without IVT did not influence their outcomes (crude OR = 0.74, 95% CI = [0.31-1.78]). Discussion: A perfusion lesion of ≥65 mL predicted poor functional outcome in mild stroke patients with LVO.]]> Wed 28 Feb 2024 15:56:25 AEDT ]]> Comparing Explainable Machine Learning Approaches With Traditional Statistical Methods for Evaluating Stroke Risk Models: Retrospective Cohort Study. https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52405 Wed 28 Feb 2024 15:54:25 AEDT ]]> Management of post-stroke fatigue: an Australian health professional survey https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53952 Wed 28 Feb 2024 15:24:26 AEDT ]]> Management of Poststroke Hyperglycemia: Results of the TEXAIS Randomized Clinical Trial https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54324 Wed 28 Feb 2024 15:22:19 AEDT ]]> A phase III, multi-arm multi-stage covariate-adjusted response-adaptive randomized trial to determine optimal early mobility training after stroke (AVERT DOSE) https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51317  2) and hemorrhagic stroke. With four arms per stratum (reference arm retained throughout), only the single treatment arm demonstrating the highest proportion of favorable outcomes at the first stage will proceed to the second stage in each stratum, resulting in a final comparison with the reference arm. Three prognostic covariates of age, geographic region and reperfusion interventions, as well as previously observed mRS 0-2 responses inform the adaptive randomization procedure. Participants randomized receive prespecified mobility training regimens (functional task-specific), provided by physiotherapists/nurses until discharge or 14 days. Interventions replace usual mobility training. Fifty hospitals in seven countries (Australia, Malaysia, United Kingdom, Ireland, India, Brazil, Singapore) are expected to participate. Summary: Our novel adaptive trial design will evaluate a wider variety of mobility regimes than a traditional two-arm design. The data-driven adaptions during the trial will enable a more efficient evaluation to determine the optimal early mobility intervention for patients with mild and moderate ischemic stroke.]]> Wed 28 Feb 2024 15:05:25 AEDT ]]> A Scoping Review of mHealth Interventions for Secondary Prevention of Stroke: Implications for Policy and Practice https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53492 Wed 28 Feb 2024 15:04:18 AEDT ]]> A roadmap for research in post-stroke fatigue: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54154 Wed 28 Feb 2024 15:02:37 AEDT ]]> A Method for Rapid Machine Learning Development for Data Mining with Doctor-inthe- Loop https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50396 Wed 28 Feb 2024 15:00:05 AEDT ]]> Blood-brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes? https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45212 Wed 26 Oct 2022 15:56:18 AEDT ]]> Hospital staff, volunteers' and patients' perceptions of barriers and facilitators to communication following stroke in an acute and a rehabilitation private hospital ward: a qualitative description study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45255 Wed 26 Oct 2022 15:34:30 AEDT ]]> Astrocyte activation in neurovascular damage and repair following ischaemic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45205 Wed 26 Oct 2022 14:39:16 AEDT ]]> i-Rebound after stroke-eat for health: mediterranean dietary intervention co-design using an integrated knowledge translation approach and the TIDieR checklist https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45085 n = 6), specialist dietitians (n = 6) and an IKT research team (n = 8) participated in a 4-phase co-design process. Phase 1: the IKT team developed the research questions, and identified essential program elements and workshop strategies for effective co-design. Phase 2: Participant co-design workshops used persona and journey mapping to create user profiles to identify barriers and essential program elements. Phase 3: The IKT team mapped Phase 2 data to the TIDieR checklist and developed the intervention prototype. Phase 4: Co-design workshops were conducted to refine the prototype for trial. Rigorous IKT co-design fundamentally influenced intervention development. Modifications to the protocol based on participant input included ensuring that all resources were accessible to people with aphasia, an additional support framework and resources specific to outcome of stroke. The feasibility and safety of this intervention is currently being pilot tested (randomised controlled trial; 2019/ETH11533, ACTRN12620000189921).]]> Wed 26 Oct 2022 12:25:58 AEDT ]]> Feasibility of national living guideline methods: The Australian Stroke Guidelines https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47114 Wed 22 Mar 2023 19:03:52 AEDT ]]> The long-term unmet needs of informal carers of stroke survivors at home: a systematic review of qualitative and quantitative studies https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44465 Wed 22 Feb 2023 13:51:07 AEDT ]]> Depression and a lack of socialization are associated with high levels of boredom during stroke rehabilitation: An exploratory study using a new conceptual framework https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48925 Wed 19 Apr 2023 15:49:30 AEST ]]> People with Stroke Are Most Sedentary in the Afternoon and Evening https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47104 Wed 14 Dec 2022 09:58:30 AEDT ]]> Stroke survivors’ perceptions of the factors that influence engagement in activity outside dedicated therapy sessions in a rehabilitation unit: A qualitative study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51671 Wed 13 Sep 2023 10:07:41 AEST ]]> Investigating deep brain stimulation as a tool to prevent secondary neurodegeneration following stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:41832 Wed 13 Mar 2024 13:54:31 AEDT ]]> An equity evaluation in stroke inpatients in regard to medical costs in China: a nationwide study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45248 P < 0.05), but have no impact on average length of stay. Conclusions: China's fragmented urban health insurance schemes require further reform to ensure better equity in healthcare utilization and medical costs for stroke patients. Improving education attainment, offering equal access to healthcare, allocating health resources reasonably and balancing health services prices in different regions also count.]]> Wed 13 Mar 2024 08:53:14 AEDT ]]> Bringing CT Scanners to the Skies: Design of a CT Scanner for an Air Mobile Stroke Unit https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47959 Wed 13 Mar 2024 07:52:44 AEDT ]]> Neuroinflammation as a key driver of secondary neurodegeneration following stroke? https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53699 Wed 10 Jan 2024 10:48:23 AEDT ]]> Breaking up prolonged sitting time after stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:41830 Wed 06 Mar 2024 15:30:17 AEDT ]]> Intracranial pressure elevation and cerebrospinal fluid change after ischaemic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48391 Wed 06 Mar 2024 15:05:26 AEDT ]]> Elucidating the mechanisms involved in intracranial pressure elevation and hypothermia treatment for ischaemic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48390 Wed 06 Mar 2024 15:01:17 AEDT ]]> Neurofilament light chain (Nfl) in blood—a biomarker predicting unfavourable outcome in the acute phase and improvement in the late phase after stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50139 Wed 05 Jul 2023 12:54:49 AEST ]]> Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52178 Wed 04 Oct 2023 11:05:28 AEDT ]]> Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54067 Tue 30 Jan 2024 13:56:39 AEDT ]]> Prevalence and Impact of Poststroke Fatigue on Patient Outcomes in the First 6 Months After Stroke: A Systematic Review and Meta-analysis https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54548 Tue 27 Feb 2024 20:42:16 AEDT ]]> Outcome after acute ischemic stroke is linked to sex-specific lesion patterns https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43840 Tue 21 Mar 2023 17:30:07 AEDT ]]> Most endovascular thrombectomy patients have Target Mismatch despite absence of formal CT perfusion selection criteria https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54333 1.8. The primary outcome was good functional outcome at 90 days, defined as a modified Rankin Scale (mRS) score 0-2. follow-up infarct volume, core expansion and penumbral salvage volumes were secondary outcomes. Of 572 anterior circulation EVT patients, CTP source image data required to generate objective maps were available in 170, and a Target Mismatch was present in 151 (89%). The rate of 90-day good functional outcome was similar between Target Mismatch (53%) and Large Core Non-Mismatch groups (46%, p = 0.629). Median follow-up infarct volume in the Large Core Non-Mismatch group (104ml [IQR 25ml-189ml]) was larger than that in the Target Mismatch patients (16ml [8ml-47ml], p<0.001). Despite a lack of formal CTP selection criteria, the majority of patients treated at our centres had a Target Mismatch. Patients without Target Mismatch had larger follow-up infarct volumes, but the functional recovery rate was similar to that in Target Mismatch patients. Infarct volumes should be included as objective assessment criteria in the evaluation of the efficacy of EVT in non-Target Mismatch patients.]]> Tue 20 Feb 2024 16:05:37 AEDT ]]> Ultra-Long Transfers for Endovascular Thrombectomy - Mission Impossible?: The Australia-New Zealand Experience https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50318 300 miles would benefit from EVT, achieving rates of functional independence (modified Rankin Scale [mRS] score of 0-2) at 3 months similar to those patients treated at the comprehensive stroke center in the randomized EVT extended window trials and that the selection of patients with computed tomography perfusion (CTP) at the referring site would be associated with ordinal shift toward better outcomes on the mRS. Methods: This is a retrospective analysis of patients transferred from 31 referring hospitals >300 miles (measured by the most direct road distance) to 9 comprehensive stroke centers in Australia and New Zealand for EVT consideration (April 2016 through May 2021). Results: There were 131 patients; the median age was 64 [53-74] years and the median baseline National Institutes of Health Stroke Scale score was 16 [12-22]. At baseline, 79 patients (60.3%) had noncontrast CT+CT angiography, 52 (39.7%) also had CTP. At the comprehensive stroke center, 114 (87%) patients underwent cerebral angiography, and 96 (73.3%) proceeded to EVT. At 3 months, 62 patients (48.4%) had an mRS score of 0 to 2 and 81 (63.3%) mRS score of 0 to 3. CTP selection at the referring site was not associated with better ordinal scores on the mRS at 3 months (mRS median of 2 [1-3] versus 3 [1-6] in the patients selected with noncontrast CT+CT angiography, P=0.1). Nevertheless, patients selected with CTP were less likely to have an mRS score of 5 to 6 (odds ratio 0.03 [0.01-0.19]; P<0.01). Conclusions: In selected patients transferred >300 miles, there was a benefit for EVT, with outcomes similar to those treated in the comprehensive stroke center in the EVT extended window trials. Remote hospital CTP selection was not associated with ordinal mRS improvement, but was associated with fewer very poor 3-month outcomes.]]> Tue 18 Jul 2023 14:30:07 AEST ]]> Diagnostic Utility of Computed Tomography Perfusion in the Telestroke Setting https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52537 Tue 17 Oct 2023 10:04:45 AEDT ]]> Growth hormone and neuronal hemoglobin in the brain-roles in neuroprotection and neurodegenerative diseases https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46328 Tue 15 Nov 2022 12:30:40 AEDT ]]> Length of Stay, Hospital Costs and Mortality Associated With Comorbidity According to the Charlson Comorbidity Index in Immobile Patients After Ischemic Stroke in China: A National Study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47080 Tue 13 Dec 2022 16:28:32 AEDT ]]> Whole blood viscosity is associated with baseline cerebral perfusion in acute ischemic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47058 Tue 13 Dec 2022 15:32:44 AEDT ]]> Dural arteriovenous fistulas in cerebral venous thrombosis: Data from the International Cerebral Venous Thrombosis Consortium https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47048 30 days: 39% vs. 7%; p < 0.001) and sigmoid sinus thrombosis (86% vs. 51%; p < 0.001), and less frequently had parenchymal lesions (31% vs. 55%; p = 0.013) at baseline imaging. Clinical outcome at last follow-up did not differ between patients with and without dAVF. Additionally, five patients were confirmed with dAVF from non-consecutive CVT cohorts. Among all patients with CVT and dAVF, 17/34 (50%) had multiple fistulas and 23/34 (68%) had cortical venous drainage. Of 34 patients with dAVF with 36 separate CVT events, 3/36 fistulas (8%) were diagnosed prior to, 20/36 (56%) simultaneously and 13/36 after (36%, median 115 [IQR 38–337] days) diagnosis of CVT. Conclusions: Dural arteriovenous fistulas occur in at least 2% of CVT patients and are associated with chronic CVT onset, older age and male sex. Most CVT-related dAVFs are detected simultaneously or subsequently to diagnosis of CVT.]]> Tue 13 Dec 2022 14:44:16 AEDT ]]> Impact of an outpatient telestroke clinic on management of rural stroke patients https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46988 Tue 13 Dec 2022 09:28:29 AEDT ]]> Staff and volunteers' perceptions of a Communication Enhanced Environment model in an acute/slow stream rehabilitation and a rehabilitation hospital ward: a qualitative description study within a before-and-after pilot study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52359 Tue 10 Oct 2023 09:15:40 AEDT ]]> EXPRESS: A roadmap for research in post-stroke fatigue: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54146 Tue 06 Feb 2024 12:04:28 AEDT ]]> Association of Stroke Lesion Pattern and White Matter Hyperintensity Burden With Stroke Severity and Outcome https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51452 2) were modeled within purpose-built Bayesian linear and logistic regression frameworks. Interaction effects between stroke lesions and a high vs low WMH burden were integrated via hierarchical model structures. Models were adjusted for age, age2, sex, total DWI lesion and WMH volumes, and comorbidities. Data were split into derivation and validation cohorts. Results: A total of 928 patients with AIS contributed to acute stroke severity analyses (age: 64.8 [14.5] years, 40% women) and 698 patients to long-term functional outcome analyses (age: 65.9 [14.7] years, 41% women). Stroke severity was mainly explained by lesions focused on bilateral subcortical and left hemispherically pronounced cortical regions across patients with both a high and low WMH burden. Lesions centered on left-hemispheric insular, opercular, and inferior frontal regions and lesions affecting right-hemispheric temporoparietal regions had more pronounced effects on stroke severity in case of high compared with low WMH burden. Unfavorable outcomes were predominantly explained by lesions in bilateral subcortical regions. In difference to the lesion location–specific WMH effects on stroke severity, higher WMH burden increased the odds of unfavorable outcomes independent of lesion location. Discussion: Higher WMH burden may be associated with an increased stroke severity in case of stroke lesions involving left-hemispheric insular, opercular, and inferior frontal regions (potentially linked to language functions) and right-hemispheric temporoparietal regions (potentially linked to attention). Our findings suggest that patients with specific constellations of WMH burden and lesion locations may have greater benefits from acute recanalization treatments. Future clinical studies are warranted to systematically assess this assumption and guide more tailored treatment decisions.]]> Tue 05 Sep 2023 18:01:19 AEST ]]> More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43876 Tue 04 Oct 2022 12:35:43 AEDT ]]> Movement of cerebrospinal fluid tracer into brain parenchyma and outflow to nasal mucosa is reduced at 24 h but not 2 weeks post-stroke in mice https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51314 Thu 31 Aug 2023 14:29:02 AEST ]]> Comparing the physical activity of stroke survivors in high-income countries and low to middle-income countries https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:39834 Thu 28 Jul 2022 09:38:56 AEST ]]> Development of strategies to support home-based exercise adherence after stroke: A Delphi consensus https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45384 Thu 27 Oct 2022 16:12:08 AEDT ]]> Dental anxiety and oral health following stroke: a pilot study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51208 Thu 24 Aug 2023 14:59:36 AEST ]]> Primary outcomes data from a randomised controlled trial testing the effect of an online healthy lifestyles program on health-related quality of life among stroke survivors https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:38922 Thu 16 Nov 2023 12:20:26 AEDT ]]> Interventions for reducing sedentary behaviour in people with stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48855 Thu 13 Apr 2023 13:36:30 AEST ]]> Feasibility of the community-based Stay at Work Intervention (SAWI) for stroke survivors https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50913 Thu 10 Aug 2023 15:24:02 AEST ]]> Managing Urban Stroke Health Expenditures in China: Role of Payment Method and Hospital Level https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52260 Thu 05 Oct 2023 14:20:44 AEDT ]]> A narrative review of stroke incidence, risk factors and treatment in Indigenous Peoples of the world https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:38784 Mon 31 Jan 2022 14:00:24 AEDT ]]> Factors influencing sedentary time and physical activity early after stroke: a qualitative study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43639 Mon 26 Sep 2022 16:36:52 AEST ]]> Self-reported quality of life following stroke: a systematic review of instruments with a focus on their psychometric properties https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44765 Mon 24 Oct 2022 08:49:52 AEDT ]]> Altering the rehabilitation environment to improve stroke survivor activity: A Phase II trial https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49585 Mon 22 May 2023 12:22:22 AEST ]]> Endovascular Thrombectomy Versus Medical Management in Isolated M2 Occlusions: Pooled Patient-Level Analysis from the EXTEND-IA Trials, INSPIRE, and SELECT Studies https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48932 Mon 17 Apr 2023 15:37:11 AEST ]]> How FAST are we? A systematic review and meta-analysis of the effectiveness of intervention done on paramedic services in increasing thrombolysis rate https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52511 Mon 16 Oct 2023 10:31:18 AEDT ]]> How frequently should “living” guidelines be updated? Insights from the Australian Living Stroke Guidelines https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52512 Mon 16 Oct 2023 10:31:07 AEDT ]]> Conservative or liberal oxygen therapy for mechanically ventilated adults with acute brain pathologies: A post-hoc subgroup analysis https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47387 Mon 16 Jan 2023 15:31:37 AEDT ]]> Clopidogrel Administration Impairs Post-Stroke Learning and Memory Recovery in Mice https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50905 Mon 13 Nov 2023 08:50:41 AEDT ]]> Non-therapeutic strategies to promote physical activity of stroke survivors in hospital settings: A systematic review https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53030 Mon 13 Nov 2023 08:50:28 AEDT ]]> Comparison of two pre-hospital stroke scales to detect large vessel occlusion strokes in Australia: A prospective observational study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46980 Mon 12 Dec 2022 17:01:27 AEDT ]]> The Hospitalization Rate of Cerebral Venous Sinus Thrombosis before and during COVID-19 Pandemic Era: A Single-Center Retrospective Cohort Study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46977 50-year-old were more often hospitalized in the COVID-19 period (P = 0.042). SARS-CoV-2 PCR test was done in 49.3% out of all COVID-19 period patients, which were positive in 6.5%. Modified Rankin Scale (mRS) score ≥3 at three-month follow-up was associated with age (P = 0.015) and malignancy (P = 0.014) in pre-COVID period; and was associated with age (P = 0.025), altered mental status on admission time (P<0.001), malignancy (P = 0.041) and COVID-19 infection (P = 0.008) in COVID-19 period. Conclusion: Since there was a more dismal outcome in COVID-19 associated CVST, a high index of suspicion for CVST among COVID-19 positive is recommended.]]> Mon 12 Dec 2022 17:01:24 AEDT ]]> Scoping Review of Available Culinary Nutrition Interventions for People with Neurological Conditions https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54750 Mon 11 Mar 2024 14:46:47 AEDT ]]> Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies. https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54738 Mon 11 Mar 2024 14:19:10 AEDT ]]> Narratives of illness and recovery: (re)constructing continuity in life after stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54172 Mon 11 Mar 2024 12:10:28 AEDT ]]> Quality of life and mood disorders of mild to moderate stroke survivors in the early post-hospital discharge phase: a cross-sectional survey study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50230 Mon 10 Jul 2023 14:00:54 AEST ]]> Delayed filling of the superficial middle cerebral vein in acute large artery occlusion https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52319 Mon 09 Oct 2023 10:25:02 AEDT ]]> How little is enough? The feasibility of conducting a dose-escalation study for exercise training in people with stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52271 Mon 09 Oct 2023 10:04:07 AEDT ]]> Access to and Use of Internet and Social Media by Low-Morbidity Stroke Survivors Participating in a National Web-Based Secondary Stroke Prevention Trial: Cross-sectional Survey https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48223 75 years were significantly less likely to use social media compared with those aged <55 years (adjusted odds ratio 0.17, 95% CI 0.07-0.44). Health risk factors were not found to be associated with searching for health- or medical-related information. Conclusions: The internet appears to be a viable platform to engage with stroke survivors who may not be high-morbidity to conduct research and provide information and health interventions. This is important given that they are at high risk of recurrent stroke regardless of their level of disability. Exploring the technology use behaviors and the possibility of eHealth among survivors who experience higher levels of morbidity or disability because of their stroke is an area of research that warrants further study.]]> Mon 08 May 2023 10:35:04 AEST ]]> Age-Related Disparities in the Quality of Stroke Care and Outcomes in Rehabilitation Hospitals: The Australian National Audit https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40197 Mon 08 Aug 2022 13:29:07 AEST ]]> Investigation of the implementation of a Communication Enhanced Environment model on an acute/slow stream rehabilitation and a rehabilitation ward: A before-and-after pilot study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46803 Mon 05 Dec 2022 08:36:25 AEDT ]]> Long-term effect of additional rehabilitation following botulinum toxin-A on upper limb activity in chronic stroke: the InTENSE randomised trial https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51414 Mon 04 Sep 2023 14:52:01 AEST ]]> Measures of Maximal Tactile Pressures during a Sustained Grasp Task Using a TactArray Device Have Satisfactory Reliability and Concurrent Validity in People with Stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51413 Mon 04 Sep 2023 14:50:35 AEST ]]> Evaluation of an online intervention for improving stroke survivors’ health-related quality of life: A randomised controlled trial https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51394 Mon 04 Sep 2023 14:43:12 AEST ]]> How Should We Measure Physical Activity After Stroke? An International Consensus https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:53533 Mon 04 Dec 2023 15:37:40 AEDT ]]> Health care utilization for patients with stroke: a 3-year cross-sectional study of China's two urban health insurance schemes across four cities https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:39215 Fri 27 May 2022 11:16:33 AEST ]]> Stroke survivor, caregiver and therapist experiences of home-based stroke rehabilitation: a thematic synthesis of qualitative studies https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51591 Fri 22 Sep 2023 13:48:17 AEST ]]> Increased Relative Functional Gain and Improved Stroke Outcomes: A Linked Registry Study of the Impact of Rehabilitation https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51912 Fri 22 Sep 2023 10:40:45 AEST ]]> Interventions for the uptake of evidence-based recommendations in acute stroke settings https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52657 Fri 20 Oct 2023 09:10:15 AEDT ]]> Evaluating the feasibility and acceptability of the Mood Assessment Post-Stroke (MAPS) mood screening training https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54843 Fri 15 Mar 2024 15:08:40 AEDT ]]> Reactive astrocytes prevent maladaptive plasticity after ischemic stroke https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47354 Fri 13 Jan 2023 13:20:00 AEDT ]]> Association of Endovascular Thrombectomy With Functional Outcome in Patients With Acute Stroke With a Large Ischemic Core. https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:47319 70mL. We aimed to compare outcomes of EVT and non-EVT patients with an ischemic core≥70mL, hypothesizing that there would be a benefit from EVT for fair outcome (three-month modified Rankin Scale, mRS, 0-3) after stroke. METHODS: Retrospective analysis of patients enrolled into a multi-center (Australia, China and Canada) registry (2012-2020) who underwent CTP within 24 hours of stroke onset and had a baseline ischemic core≥70mL. Primary outcome was the estimation of the association of EVT in patients with core volume ≥70mL, as well as within 70-100mL and ≥100mL subgroups with fair outcome. RESULTS: Of the 3283 patients in the registry, 299 had CTP core≥70 mL and 269 complete data (135 had core volume between 70-100mL and 134≥100mL). EVT was performed in 121(45%) patients. EVT-treated patients were younger (median 69 versus 75 years; p=0.011), had lower pre-stroke mRS, and smaller median core volumes, 92[79-116.5]mL versus 105.5[85.75-138]mL, (p=0.004). EVT-treated patients had higher odds of achieving fair outcome in adjusted analysis (30% versus 13.9% in the non-EVT group; aOR 2.1(95% CI 1, 4.2), p=0.038). The benefit was seen predominantly in those with 70-100mL core (71 /135 (52.6%) EVT-treated), with 54.3% in EVT-treated versus 21% in non-EVT group achieving a fair outcome (aOR 2.5 (95% CI 1, 6.2), p=0.005). Of those with a core≥100mL, 50 /134(37.3%) underwent EVT. Proportions of fair outcome were very low in both groups (8.1% versus 8.7%; p=0.908). DISCUSSION: We found a positive association of EVT with 3-month outcome after stroke in patients with a baseline CTP ischemic core volume 70-100 mL but not in those with ≥100 mL. Randomized data to confirm these findings is required. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that EVT is associated with better motor outcomes 3 months following CTP-defined ischemic stroke with core of 70-100 mL.]]> Fri 13 Jan 2023 11:06:45 AEDT ]]> Look Before You Leap: Interventions Supervised via Telehealth Involving Activities in Weight-Bearing or Standing Positions for People After Stroke-A Scoping Review https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49426 Fri 12 May 2023 15:16:21 AEST ]]> Blood pressure excursions in acute ischemic stroke patients treated with intravenous thrombolysis https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46103 185/105 mmHg) during the first 24 h following tPA-bolus. The majority of BP excursions (46%) occurred within the first 75 min from tPA-bolus. Patients with at least one BP excursion in the first 24 h following tPA bolus had significantly lower rates of independent functional outcome at 90 days (31 vs. 40.1%, P = 0.028). The total number of BP excursions was associated with decreased odds of 24-h clinical recovery (OR = 0.88, 95% CI:0.80–0.96), 24-h neurological improvement (OR = 0.87, 95% CI: 0.81–0.94), 7-day functional improvement (common OR = 0.92, 95% CI: 0.87–0.97), 90-day functional improvement (common OR = 0.94, 95% CI: 0.88–0.98) and 90-day independent functional outcome (OR = 0.90, 95% CI: 0.82–0.98) in analyses adjusted for potential confounders. DBP excursions were independently associated with increased odds of any intracranial hemorrhage (OR = 1.26, 95% CI: 1.04–1.53). Conclusion: BP excursions above guideline thresholds during the first 24 h following tPA administration for AIS are common and are independently associated with adverse clinical outcomes.]]> Fri 11 Nov 2022 15:33:52 AEDT ]]> Effects of therapy with a free-standing robotic exoskeleton on motor function and other health indicators in people with severe mobility impairment due to chronic stroke: A quasi-controlled study https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40334 Fri 08 Jul 2022 09:51:43 AEST ]]> A qualitative study of sedentary behaviours in stroke survivors: non-participant observations and interviews with stroke service staff in stroke units and community services https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49170 Fri 05 May 2023 15:37:23 AEST ]]> Impairments, and physical design and culture of a rehabilitation unit influence stroke survivor activity: qualitative analysis of rehabilitation staff perceptions https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49113 Fri 05 May 2023 11:39:23 AEST ]]> Utilizing the intelligence edge framework for robotic upper limb rehabilitation in home https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:52973 Fri 03 Nov 2023 15:31:29 AEDT ]]>