https://novaprd-lb.newcastle.edu.au/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46711 n = 80), intermediate second language (L2) Mandarin learners (n = 40), and L1 Mandarin speakers (n = 40) took part in a multiday Mandarin-like artificial language learning task. Participants were asked to repeat a syllable–tone combination immediately after hearing it. Half of all participants were exposed to speech from 1 talker (low variability) while the other half heard speech from 4 talkers (high variability). Half of the L1 English participants were given daily explicit instruction on Mandarin tone contours, while the other half were not. Tone accuracy was measured by L1 Mandarin raters (n = 104) who classified productions according to their perceived tonal category. Explicit instruction of tone contours facilitated L1 English participants’ production of rising and falling tone contours. High variability input alone had no main effect on participants’ productions but interacted with explicit instruction to improve participants’ productions of high-level tone contours. These results motivate an L2 tone production training approach that consists of explicit tone instruction followed by gradual exposure to more variable speech.]]> Wed 29 Mar 2023 12:32:34 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40569 Wed 29 Mar 2023 12:09:59 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54979 Wed 27 Mar 2024 09:31:09 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:35627 Wed 24 Nov 2021 15:52:05 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42533 Wed 24 Aug 2022 15:50:24 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42518 Wed 24 Aug 2022 11:55:03 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:27361 Wed 23 Feb 2022 16:04:23 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43499 Wed 21 Sep 2022 10:05:07 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:40773 Western Australian Study in Reading Aloud (WASRA) collected data from over 100 teachers at 14 Australian schools. The WASRA reveals tensions in translating reading aloud practices into daily practice due to reported lack of time and high curriculum demands. The findings suggest that primary school teachers typically enjoy reading aloud to children, though fewer enjoyed reading themselves. Recommendations are provided to address time and curriculum demands purported as being inhibitors of daily reading practices. These recommendations go some way to help mitigate against literacy inequities within our primary classrooms and in so doing encourage provision of daily reading opportunities for teachers and reading aloud practices.]]> Wed 20 Jul 2022 09:49:28 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42330 Wed 17 Apr 2024 09:55:49 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42880 Wed 13 Mar 2024 08:53:37 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42527 Wed 13 Mar 2024 08:49:07 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36528 Wed 10 Nov 2021 15:13:07 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49861 Wed 07 Jun 2023 13:41:43 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42093 Wed 07 Feb 2024 17:19:01 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46917 Wed 07 Dec 2022 10:12:30 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:54641 Wed 06 Mar 2024 18:47:59 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34432 Wed 06 Apr 2022 14:03:47 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:35216 .05). Conclusion: White matter changes after stroke may be localized rather than a global phenomenon.]]> Wed 06 Apr 2022 13:57:07 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:35891 3 months attending diabetes centres in Newcastle, Australia. Rates of overweight and obesity were compared with matched population survey results. Results: Data from 308 youth and 283 young adults were included. In girls, significantly higher prevalence of overweight and obesity were seen in the 5–8 (43% vs. 18%), 13–16 (41% vs. 27%), 18–24 (46% vs. 34%) and 25–30 (60% vs. 43%) years age groups; whereas in boys increased prevalence was observed in the 5–8 years age group only (41% vs. 18%). Rates of overweight and obesity increased with age across sexes. In youth, BMI standard deviation score was correlated with socio‐economic status, insulin regimen, blood pressure and blood lipids (P < 0.05). In adults, BMI was positively associated with blood pressure, and longer diabetes duration (P < 0.02). Conclusions: Overweight and obesity are over‐represented in young persons with type 1 diabetes, particularly girls. As overweight is associated with other cardiovascular disease markers early intervention is paramount.]]> Wed 06 Apr 2022 13:57:00 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44005 Wed 05 Oct 2022 14:57:34 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49046 Wed 03 May 2023 14:09:00 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:32635 Wed 02 Sep 2020 16:45:12 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:32634 Wed 02 Sep 2020 16:30:18 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45577 Wed 02 Nov 2022 08:16:57 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50728 Tue 29 Aug 2023 10:49:44 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:51154 Tue 29 Aug 2023 10:05:28 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44922 n=11) were rated weak to moderate in methodological quality. Nine published papers, four unique studies, examined staff reported provision of smoking cessation care; eight reported an increase, one found no change. Three papers, two unique studies, examined client receipt of care; all found significant increases. Three papers, two unique studies, assessed staff smoking prevalence from pre- to post-intervention. Only one study reported a significant reduction in staff smoking prevalence (35.2 versus 21.8%, P=0.005). Nine papers, six unique studies, assessed client smoking cessation and smoking-related outcomes. Seven papers reported on client smoking prevalence; two found a significant decrease and five found no change to smoking. Four papers reported on number of cigarettes per day, three found a significant decrease and one found no change. Two papers reported on smoking cessation finding a 10% and a 25% seven-day point prevalence abstinence post-discharge from the AOD service. Conclusions: Organizational change interventions within health-care services to make smoking cessation care delivery part of usual treatment offer promise for increasing smoking cessation care and reducing smoking prevalence.]]> Tue 25 Oct 2022 09:40:31 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36646 Tue 23 Jun 2020 09:22:45 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48538 Tue 21 Mar 2023 15:23:57 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44634 Tue 18 Oct 2022 14:48:30 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37696 Tue 16 Mar 2021 17:37:59 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43170 Tue 13 Sep 2022 16:03:51 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37666 Choerodon rubescens in marine waters of the outer reefs in the World Heritage Area of Shark Bay (26° S; 114° E) and of Choerodon schoenleinii in inner protected reefs of that large embayment. The dietary compositions of C. rubescens and C. schoenleinii differed significantly among length classes, progressed serially with increasing body size, both overall and almost invariably in each season and were more closely related to body size than season, whose effect was at best minimal. The size‐related dietary change in C. rubescens involved, in particular, a shift from crustaceans and non‐mytilid bivalves to mytilid bivalves and echinoid echinoderms. Although the diet of C. schoenleinii followed similar size‐related changes, it contained a greater volume of gastropods when the fish were small and mytilids when large and only a small volume of echinoids. The dietary composition of C. rubescens in the Abrolhos Islands, 300 km to the south of Shark Bay, was related both to length class and season and differed from that of this labrid in Shark Bay with the ingestion of lesser volumes of mytilids and greater volumes of echinoids. The size‐related changes in diet imply that these species shift from foraging over soft substrata to over reefs as their very well‐developed jaws become sufficiently strong to remove attached and larger prey. The dietary compositions of C. rubescens and C. schoenleinii in Shark Bay and of C. rubescens at the Abrolhos Islands were related far more to habitat–locational differences than to length class and season. The above intraspecific and interspecific differences in diet are consistent with qualitative accounts of the relative abundances of the main prey in their respective environments, supporting the view that, despite specializations in their feeding apparatus, these labrids can feed opportunistically to a certain extent and could thus potentially respond to moderate changes in the composition of their prey caused by climate change and other anthropogenic effects.]]> Tue 09 Mar 2021 18:05:52 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44763 Pseudomonas is a large and diverse genus of Gammaproteobacteria. To provide a framework for discovery of evolutionary and taxonomic relationships of these bacteria, we compared the genomes of type strains of 163 species and 3 additional subspecies of Pseudomonas, including 118 genomes sequenced herein. A maximum likelihood phylogeny of the 166 type strains based on protein sequences of 100 single-copy orthologous genes revealed thirteen groups of Pseudomonas, composed of two to sixty three species each. Pairwise average nucleotide identities and alignment fractions were calculated for the data set of the 166 type strains and 1224 genomes of Pseudomonas available in public databases. Results revealed that 394 of the 1224 genomes were distinct from any type strain, suggesting that the type strains represent only a fraction of the genomic diversity of the genus. The core genome of Pseudomonas was determined to contain 794 genes conferring primarily housekeeping functions. The results of this study provide a phylogenetic framework for future studies aiming to resolve the classification and phylogenetic relationships, identify new gene functions and phenotypes, and explore the ecological and metabolic potential of the Pseudomonas spp.]]> Tue 08 Nov 2022 11:16:28 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42887 cut(kinetic) was set at 500, 200, and 10 keV, and differences between 1 and 3 mm voxel were calculated. A planning study with 10 patient stereotactic body radiotherapy (SBRT) spine plans and 10 patient H&N plans was calculated in both Acuros XB (AXB) v15.6.06 and Anisotropic Analytical Algorithm (AAA) v15.6.06. The patient contour was overridden to water as only the penumbral differences between the two different algorithms were under investigation. Results: The dosimetry audit results show that for the SBRT spine case, plans calculated in AXB are colder than what is measured in the spinal cord by 5%-10%. This was also observed for other audit cases where a C-shape target is wrapped around an OAR where the plans were colder by 3%-10%. Plans calculated with Monaco MC were colder than measurements by approximately 7% with the OAR surround by a C-shape target, but these differences were not noted in the SBRT spine case. Results from the clinical patient plans showed that the AXB was on average 7.4% colder than AAA when comparing the minimum dose in the spinal cord OAR. This average difference between AXB and AAA reduced to 4.5% when using the more clinically relevant metric of maximum dose in the spinal cord. For the H&N plans, AXB was cooler on average than AAA in the spinal cord OAR (1.1%), left parotid (1.7%), and right parotid (2.3%). The EGSnrc investigation also noted similar, but smaller differences. The beam penumbra modeled by E_cut(kinetic) = 500 keV was steeper than the beam penumbra modeled by E_cut(kinetic) = 10 keV as the full scatter is not accounted for, which resulted in less dose being calculated in a central OAR region where the penumbra contributes much of the dose. The dose difference when using 2.5 mm voxels of the center of the OAR between 500 and 10 keV was 3%, reducing to 1% between 200 and 10 keV. Conclusions: Lack of full penumbral modeling due to approximations in the algorithms in MC based or LBTE algorithms are a contributing factor as to why these algorithms under-predict the dose to OAR when the treatment volume is wrapped around the OAR. The penumbra modeling approximations also contribute to AXB plans predicting colder doses than AAA in areas that are in the vicinity of beam penumbra. This effect is magnified in regions where there are many beam penumbras, for example in the spinal cord for spine SBRT cases.]]> Tue 06 Sep 2022 13:57:20 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:38998 Tue 05 Apr 2022 15:19:29 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:31199 Tue 03 Sep 2019 18:27:06 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30396 Tue 03 Sep 2019 18:01:23 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34933 Tue 03 Sep 2019 17:58:29 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37220 Tue 01 Sep 2020 18:15:55 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:24681 Tue 01 May 2018 15:44:50 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:39959 Thu 30 Jun 2022 16:21:31 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:35478 Thu 30 Jan 2020 16:34:09 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34934 Thu 28 Oct 2021 12:36:04 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30651 Thu 28 Oct 2021 12:35:58 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:33671 Thu 27 Jan 2022 15:56:16 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46445 Thu 24 Nov 2022 14:11:59 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46489 Thu 24 Nov 2022 11:52:46 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49469 Thu 18 May 2023 14:34:15 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42102 n=28) received access to an online calorie tracking program, smartphone app, three telephone counselling calls with a dietitian and written material. Women in two comparison groups (CI and C2) (n=48; n=43) were from the control (C1) and intervention (C2) arms of InFANT Extend and received no additional support. Weight and waist circumference were measured objectively. Written surveys assessed diet and physical activity. Sedentary behaviour was self-reported. Linear and logistic regression assessed changes in outcomes between groups from 9 to 18 months postpartum. Results: Mean PPWR decreased in the (I) group (-1.2kg) and the C2 group (-1.2kg), although the changes were not significant. Mean waist circumference for all groups exceeded recommendations at baseline but decreased to below recommendations for women in the (I) group (78.3cm) and significantly for the (I) group (-6.4cm) compared to C1 (-1.1cm; P=0.002) and C2 (-3.3cm; P=0.001). Changes in diet, physical activity or sedentary behaviour were not significant. Conclusions: The online intervention reported in the present study shows promise with respect to reducing waist circumference in postpartum women. Further evidence of strategies that may improve weight and related behaviours in this target group is needed.]]> Thu 18 Aug 2022 13:52:00 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34937 10 mmol/l), occurrence of maternal hypoglycaemia (BGL < 3.8 mmol/l), and incidence of neonatal hypoglycaemia (BGL ≤ 2.5 mmol/l) if betamethasone was administered within 48 h of birth. Results: The cohorts comprised 151 women (Adult‐IVI n = 86; Pregnancy‐IVI n = 65). The primary outcome was 68% time‐at‐target [95% confidence interval (CI) 64–71%) for Pregnancy‐IVI compared with 55% (95% CI 50–60%) for Adult‐IVI (P = 0.0002). Critical maternal hyperglycaemia (0% vs. 2%, P = 0.02) and hypoglycaemia (2% vs. 12%, P = 0.02) were both lower with Pregnancy‐IVI than Adult‐IVI. Neonatal hypoglycaemia was less common after Pregnancy‐IVI (29%) than after Adult‐IVI (54%, P = 0.03). A multiple logistic regression model adjusting for potential confounders gave an odds ratio for neonatal hypoglycaemia with Pregnancy‐IVI of 0.27 (95% CI 0.10–0.76, P = 0.01). Conclusions: An IVI protocol designed for pregnancy effectively controlled maternal hyperglycaemia following betamethasone administration in GDM. This is the first intervention to show a reduction in betamethasone‐associated neonatal hypoglycaemia, linked with optimum maternal glycaemic control.]]> Thu 04 Nov 2021 10:39:22 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:49083 Thu 04 May 2023 09:25:22 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37213 Thu 03 Sep 2020 11:00:14 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:38796 Thu 03 Feb 2022 12:42:36 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46472 N = 156). The parametric model accounted for both stop-signal reaction time (SSRT) and trigger failure (i.e., failures to initiate the inhibition process). The returned SSRT estimate (SSRT_EXG3) was attenuated by ≈65 ms compared to traditional nonparametric SSRT estimates (SSRT_int). The amplitude and latency of the N1 and P3 event-related potential components were derived for both stop-success and stop-failure trials and compared to behavioral estimates derived from traditional (SSRT_int) and parametric (SSRT_EXG3, trigger failure) models. Both the fronto-central N1 and P3 peaked earlier and were larger for stop-success than stop-failure trials. For stop-failure trials only, N1 peak latency correlated with both SSRT estimates as well as trigger failure and temporally coincided with SSRT_EXG3, but not SSRT_int. In contrast, P3 peak and onset latency were not associated with any behavioral estimates of inhibition for either trial type. While the N1 peaked earlier for stop-success than stop-failure trials, this effect was not found in poor task performers (i.e., high trigger failure/slow SSRT). These findings are consistent with attentional modulation of both the speed and reliability of the inhibition process, but not for poor performers. Together with the absence of any P3 onset latency effect, our findings suggest that attentional mechanisms are important in supporting speeded and reliable inhibition processes required in the stop-signal task.]]> Thu 02 Nov 2023 09:54:53 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36264 b) in natural surf zones using data from seven microtidal, wave‐dominated, sandy Australian beaches. Q_b is a critical, but rarely quantified, parameter for parametric surf zone energy dissipation models, which are commonly used as coastal management tools. Here, Q_b is quantified using a combination of remote sensing and in situ data. These data and machine learning techniques enable quantification of Q_b for a substantial data set (>330,000 waves). The results show that Q_b is a highly variable parameter with a high degree of interbeach and intrabeach variability. Such variability could be correlated to environmental parameters: tidal variations correlated with changes in Q_b of up to 70% for a given local water depth (h) on a low tide terrace beach, and increased infragravity relative to sea‐swell energy correlated to lower values of Q_b at the surf‐swash boundary. Q_b also correlates well with the Australian beach morphodynamic model: For more dissipative beaches Q_b increases rapidly in the outer surf zone, whereas for more reflective beaches Q_b increases slowly throughout the surf zone. Finally, when comparing data to existing models, three commonly used theoretical formulations for Q_b are observed to be poor predictors with errors of the order of 40%. Existing theoretical Q_b models are shown to improve (revised errors of the order of 10%) if the Rayleigh probability distribution that describes the wave height is in these models is replaced by the Weibull distribution.]]> Thu 01 Jun 2023 18:46:58 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46825 Thu 01 Dec 2022 11:01:07 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46823 Thu 01 Dec 2022 10:58:04 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46820 Thu 01 Dec 2022 09:53:46 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48476 Sun 19 Mar 2023 15:13:30 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:31149 Sat 24 Mar 2018 08:43:36 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30707 Sat 24 Mar 2018 07:34:58 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:44877 Mon 24 Oct 2022 13:15:32 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:38753 Mon 24 Jan 2022 10:35:08 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30421 Mon 23 Sep 2019 13:58:17 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30408 Mon 23 Sep 2019 12:51:41 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:27031 Mon 23 Sep 2019 12:39:49 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46712 n = 50) from six countries to explore perceptions of service user involvement in mental health nursing education. Phase two utilized these findings through consensus building to co-produce standards to support Experts by Experience involvement in mental health nursing education. Results: Three themes emerged in Phase one: enablers and barriers, practical and informational support, and emotional and appraisal support. These themes underpinned development of the standards, which reflect nine processes: induction and orientation, external supervision, supportive teamwork, preparation for teaching and assessing, “intervision,” mutual mentorship, pre- and post-debriefing, role clarity and equitable payment. Conclusions: These standards form the framework entitled; Standards for Co-production of Education (Mental Health Nursing) (SCo-PE [MHN]). Implications for Practice: The standards aim to support implementation of Expert by Experience roles in mental health nursing education.]]> Mon 23 Jan 2023 10:09:25 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42969 Mon 22 Apr 2024 14:32:28 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48513 12, X₃, and their intermediate phases of borophene; X‐ray photoelectron spectroscopy, and scanning tunneling microscopy, corroborated with density functional theory band structure calculations, validate the phase purity and the metallic nature. Borophene with excellent anchoring capabilities is used for sensing of light, gas, molecules, and strain. Hybrids of borophene as well as that of reduced borophene oxide with other 2D materials are synthesized, and the predicted superior performance in energy storage is explored. The specific capacity of borophene oxide is observed to be ≈4941 mAh g⁻¹, which significantly exceeds that of existing 2D materials and their hybrids. These freestanding borophene materials and their hybrids will create a huge breakthrough in the field of 2D materials and could help to develop future generations of devices and emerging applications.]]> Mon 20 Mar 2023 16:32:14 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43429 P ≤ .05). Only GPC showed positive correlation with all fatigue domains (r = .537, P ≤ .05). On the other hand, Glx-upper, NAA-2, GSH+Hca, and fucose-3 showed negative correlations with all fatigue domains (r = –.345 to –.580, P ≤ .05). While tyrosine showed positive correlation with MFIS (r = .499, P ≤ .05), cognitive fatigue was negatively correlated with total GSH (r = –.530, P ≤ .05). No correlations were found between lesion load or brain volumes with fatigue score. CONCLUSIONS: Our results suggest that fatigue in MS is strongly correlated with an imbalance in neurometabolites but not structural brain measurements.]]> Mon 19 Sep 2022 09:29:20 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36848 2CO₃-Na₂CO₃-K₂CO₃ eutectic is used to produce highly amorphous carbon with considerable oxygen functionalization in a process focusing on the conversion of CO₂ to value-added carbon. Electrochemical characterization of materials using multiple techniques in different electrolytes allowed for the optimization of these materials as electrochemical capacitor electrodes. Variation in capacitive performance of the investigated materials has been provided based on their physical characteristics. The synthesized carbons are hybrid materials, showing both pseudocapacitive and electric double layer contributions to the total performance. Annealing under nitrogen at 800 °C is shown to widen pores in the carbon material, resulting in an increase in medium scan rate (5-10 mV.s^-1) capacitance. A stable specific capacitance of 425 F.g^-1 is obtained at 5 mV s^-1 in 0.5 M Na₂SO₄ after 1000 cycles.]]> Mon 13 Mar 2023 14:32:38 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37466 Heterozostera nigricaulis, a common Australian species, across the Pacific Ocean to colonize South America. Location: Coastal Chile, Australia and the Pacific Ocean. Methods: Genetic analyses of H. nigricaulis collected from Chile and Australia were used to assess the relationship between the populations and levels of clonality. Ocean surface current models were used to predict the probability of propagules dispersing from south‐east Australia to central Chile and shipping data used to determine the likelihood of anthropogenic dispersal. Results: Our study infers that the seagrass H. nigricaulis dispersed from Australia across the entire width of the Pacific (c. 14,000 km) to colonize South America on two occasions. Genetic analyses reveal that these events led to two large isolated clones, one of which covers a combined area of 3.47 km². Oceanographic models estimate the arrival probability of a dispersal propagule within 3 years to be at most 0.00264%. Early shipping provides a potential alternative dispersal vector, yet few ships sailed from SE Australia to Chile prior to the first recording of H. nigricaulis and the lack of more recent and ongoing introductions demonstrate the rarity of such dispersal. Main conclusions: These findings demonstrate LDD does occur over extreme distances despite very low probabilities. The large number of propagules (100s of millions) produced over 100s of years suggests that the arrival of propagules in Chile was inevitable and confirms the importance of LDD for species distributions and community ecology.]]> Mon 11 Jan 2021 17:26:39 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42843 n = 195; untreated n = 338). Median on-study pairwise-censored follow-up was 3.4 years (quartiles 1.2–5.5). No difference in the hazard of experiencing 3-month confirmed EDSS progression events was observed between the groups [hazard ratio (HR), 1.0; 95% confidence interval (CI), 0.6–1.7, P = 0.87]. We did not find significant differences in the hazards of confirmed EDSS improvement (HR, 1.0; 95% CI, 0.6–1.6, P = 0.91) or reaching a confirmed EDSS step ≥7 (HR, 1.1; 95% CI, 0.7–1.6, P = 0.69). Conclusion: Our pooled analysis of disease-modifying agents suggests that these therapies have no substantial effect on short- to medium-term disability outcomes in PPMS.]]> Mon 05 Sep 2022 14:44:21 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:39057 Fsp³ index natural-product analogues such as imino­sugars are of paramount importance in the investigation of their biological activities and reducing the use of protecting groups is an advantageous synthetic strategy. An iso­propyl­idene group was employed towards the synthesis of seven-membered ring imino­sugars and the title compound, C₉H₁₅N₃O₅, was crystallized as an inter­mediate, in which the THF ring is twisted and the dioxolane ring adopts an envelope conformation: the dihedral angle between the rings is 67.50 (13)°. In the crystal, the hydroxyl groups participate in O—H...(O,O) and O—H...N hydrogen-bonding inter­actions, which generate chains of mol­ecules propagating parallel to the a-axis direction. There is a notable non-classical C—H...O hydrogen bond, which cross-links the [100] chains into (001) sheets.]]> Mon 02 May 2022 15:27:38 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:41322 Mon 01 Aug 2022 15:46:21 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:46545 Fri 25 Nov 2022 11:19:25 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:33067 Sargassum vestitum, Sargassum linearifolium, Phyllospora comosa, Padina sp., Hormosira banksii and Sargassum podocanthum, were investigated for the chemical profile and antioxidant activity. The results showed that the extracts H. banksii, S. vestitum and Padina sp. indicated the significantly higher total phenolic compound (TPC) and antioxidant activities (ABTS, DPPH and FRAP) compared to the other species (P < 0.05) and comparable to positive controls: butylated hydroxytoluene, ascorbic acid and alpha‐tocopherol at the concentrations (0.06–1 mg mL−1). Fucoxanthin was also found in six species and isolated for evaluating antioxidant activity. In addition, the phenolic compounds were mainly responsible for antioxidant activity of the extracts, while fucoxanthin showed quite high antioxidant activity. It is suggested that S. vestitum, H. banksii and Padina sp. have the potent for extracting bioactive components and further applications in food and pharmaceutical industries.]]> Fri 24 Aug 2018 13:45:12 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30614 Daboia russelii) envenoming is a major health issue in South Asia and causes venom-induced consumption coagulopathy (VICC). Objectives: To investigate the effects of fresh frozen plasma (FFP) and two antivenom doses in correcting VICC. Methods: We undertook an open-label randomized controlled trial in patients with VICC attwo Sri Lankan hospitals. Patients with suspected Russell’s viper bites and coagulopathy were randomly allocated (1 : 1) to high-dose antivenom (20 vials) or low-dose antivenom (10 vials) plus 4 U of FFP. The primary outcome was the proportion of patients with an International Normalized Ratio (INR) of < 2 at 6 h after antivenom administration. Secondary outcomes included anaphylaxis, major hemorrhage, death, and clotting factor recovery. Results: From 214 eligible patients, 141 were randomized: 71 to high-dose antivenom, and 70 to low-dose antivenom/FFP; five had no post-antivenom blood tests. The groups were similar except for a delay of 1 h in antivenom administration for FFP patients. Six hours after antivenom administration, 23 of 69 (33%) patients allocated to high-dose antivenom had an INR of < 2, as compared with 28 of 67 (42%) allocated to low-dose antivenom/FFP (absolute difference 8%; 95% confidence interval - 8% to 25%). Fifteen patients allocated to FFP did not receive it. Severe anaphylaxis occurred equally frequently in each group. One patient given FFP developed transfusion-related acute lung injury. Three deaths occurred in low-dose antivenom/FFP patients, including one intracranial hemorrhage. There was no difference in recovery rates of INR or fibrinogen, but there was more rapid initial recovery of factor V and FX in FFP patients. Conclusion: FFP after antivenom administration in patients with Russell’s viper bites did not hasten recovery of coagulopathy. Low-dose antivenom/FFP did not worsen VICC, suggesting that low-dose antivenom is sufficient.]]> Fri 24 Aug 2018 09:01:46 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:43571 Fri 23 Sep 2022 14:03:30 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:26804 Fri 22 Apr 2022 10:24:08 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:27032 Fri 22 Apr 2022 10:20:14 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34852 Fri 20 May 2022 15:28:54 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37574 Fri 19 Feb 2021 15:23:52 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42259 Fri 19 Aug 2022 14:19:36 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42137 Fri 19 Aug 2022 08:35:55 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48473 Fri 17 Mar 2023 17:56:40 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37357 Fri 16 Oct 2020 10:30:22 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:31960 Fri 13 Apr 2018 12:35:59 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:41727 Fri 12 Aug 2022 10:04:18 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:30021 Fri 10 Mar 2023 18:45:00 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:48162 Fri 10 Mar 2023 14:40:36 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42004 Fri 10 Mar 2023 14:19:56 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36858 Fri 10 Jul 2020 19:14:44 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:42963 Fri 09 Sep 2022 09:53:36 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:45712 Fri 04 Nov 2022 10:23:59 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:35132 Raphidiopsis raciborskii is of environmental and social concern in view of its toxicity, bloom‐forming characteristics and increasingly widespread occurrence. However, while availability of macronutrients and micronutrients such as N and Fe are critically important for the growth and metabolism of this organism, the physiological response of toxic and non‐toxic strains of R. raciborskii to varying Fe and N availabilities remains unclear. By determining physiological parameters as a function of Fe and N availability, we demonstrate that R. raciborskii growth and N₂‐fixing activity are facilitated at higher Fe availability under N₂‐limited conditions with faster growth of the CS‐506 (cylindrospermopsin‐producing) strain compared with that of CS‐509 (the non‐toxic) strain. Radiolabelled Fe uptake assays indicated that R. raciborskii acclimated under Fe‐limited conditions acquires Fe at significantly higher rates than under Fe replete conditions, principally via unchelated Fe(II) generated as a result of photoreduction of complexed Fe(III). While N₂‐fixation of both strains occurred during both day and night, the CS‐506 strain overall exhibited higher N₂‐fixing and Fe uptake rates than the CS‐509 strain under N‐deficient and Fe‐limited conditions. The findings of this study highlight that Fe availability is of significance for the ecological advantage of CS‐506 over CS‐509 in N‐deficient freshwaters.]]> Fri 03 Apr 2020 12:05:38 AEDT ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:36430 Fri 01 May 2020 10:04:03 AEST ]]> https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:37697 Fri 01 Apr 2022 09:26:23 AEDT ]]>