BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922
- Creator: Wang, Chun Yan , Guo, Su Tang , Croft, Amanda , Yan, Xu Guang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2018
BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma
- Creator: Liu, Fen , Jiang, Chen Chen , Thorne, Rick F. , Jin, Lei , Wang, Qi , Zhang, Xu Dong , Yan, Xu Guang , Tseng, Hsin-Yi , Wang, Chun Yan , Zhang, Yuan Yuan , Yari, Hamed , La, Ting , Farrelly, Margaret , Guo, Su Tang
- Resource Type: journal article
- Date: 2017
BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma
- Creator: Liu, Fen , Jiang, Chen Chen , Thorne, Rick F. , Jin, Lei , Wang, Qi , Zhang, Xu Dong , Yan, Xu Guang , Tseng, Hsin-Yi , Wang, Chun Yan , Zhang, Yuan Yuan , Yari, Hamed , La, Ting , Farrelly, Margaret , Guo, Su Tang
- Resource Type: journal article
- Date: 2017
Inhibition of HSP90 by AUY922 preferentially kills mutant KRAS colon cancer cells by activating Bim through ER stress
- Creator: Wang, Chun Yan , Guo, Su Tang , Wang, Jia Yu , Liu, Fen , Zhang, Yuan Yuan , Yari, Hamed , Yan, Xu Guang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen
- Resource Type: journal article
- Date: 2016
Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922
- Creator: Wang, Chun Yan , Guo, Su Tang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen , Wang, Jia Yu , Yan, Xu Guang , Farrelly, Margaret , Zhang, Yuan Yuan , Liu, Fen , Yari, Hamed , La, Ting , Lei, Fu Xi
- Resource Type: journal article
- Date: 2016
Reactive oxygen species dictate the apoptotic response of melanoma cells to TH588
- Creator: Wang, Jia Yu , Jin, Lei , La, Ting , McFarlane, Jennifer , Lei, Fu Xi , Tabatabaee, Hessam , Chen, Jie Zhong , Croft, Amanda , Jiang, Chen Chen , Zhang, Xu Dong , Yan, Xu Guang , Sherwin, Simonne , Farrelly, Margaret , Zhang, Yuan Yuan , Liu, Fen , Wang, Chun Yan , Guo, Su Tang , Yari, Hamed
- Resource Type: journal article
- Date: 2016
INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas
- Creator: Chi, Meng Na , Guo, Su Tang , Croft, Amanda , Hondermarck, Hubert , Scolyer, Richard A. , Jiang, Chen Chen , Zhang, Xu Dong , Wilmott, James S. , Guo, Xiang Yun , Yan, Xu Guang , Wang, Chun Yan , Liu, Xiao Ying , Jin, Lei , Tseng, Hsin-Yi , Liu, Tao
- Resource Type: journal article
- Date: 2015
RIP1 kinase is an oncogenic driver in melanoma
- Creator: Liu, Xiao Ying , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Yan, Xu Guang , Jiang, Chen Chen , Guo, Su Tang , Wang, Chun Yan , Croft, Amanda , Tseng, Hsin-Yi , Wilmott, James S. , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2015