Androgen receptor is dispensable for x-zone regression in the female adrenal but regulates post-partum corticosterone levels and protects cortex integrity
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, Ian J. , Jørgensen, Anne , Frederiksen, Hanne , Curley, Michael , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2021
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
- Creator: Rebourcet, Diane , Mackay, Rosa , Darbey, Annalucia , Curley, Michael K. , Jørgensen, Anne , Frederiksen, Hanne , Mitchell, Rod T. , O'Shaughnessy, Peter J. , Nef, Serge , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging
- Creator: Curley, Michael , Milne, Laura , Smith, Sarah , Jørgensen, Anne , Frederiksen, Hanne , Hadoke, Patrick , Potter, Paul , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, J. Ian , Jørgensen, Anne , Frederiksen, Hanne , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads
- Creator: Macdonald, Joni , Kilcoyne, Karen R. , Sharpe, Richard M. , Kavanagh, Áine , Anderson, Richard A. , Brown, Pamela , Smith, Lee B. , Jørgensen, Anne , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2018