The Promise of Single-cell Technology in Providing New Insights into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia

- Pearson, Holly C. L., Hunt, Kooper V., Trahair, Toby N., Lock, Richard B., Lee, Heather J., de Bock, Charles E.

Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

- Tremblay, Cedric S., Chiu, Sung Kai, Saw, Jesslyn, McCalmont, Hannah, Litalien, Veronique, Boyle, Jacqueline, Sonderegger, Stefan E., Chau, Ngoc, Evans, Kathryn, Cerruti, Loretta, Salmon, Jessica M., McCluskey, Adam, Lock, Richard B., Robinson, Phillip J., Jane, Stephen M., Curtis, David J.

A Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia

- Krivtsov, Andrei V., Evans, Kathryn, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Gadrey, Jayant Y., Teicher, Beverley A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara

T-cell acute lymphoblastic leukemia express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

- de Bock, Charles E., Down, Michelle, Baidya, Kinsha, Sweron, Bram, Boyd, Andrew W., Fiers, Mark, Burns, Gordon F., Molloy, Timothy J., Lock, Richard B., Soulier, Jean, Taghon, Tom, Van Vlierberghe, Pieter, Cools, Jan, Holst, Jeff, Thorne, Rick F.

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

- Smith, Amanda M., Dun, Matthew D., Toop, Hamish, Lock, Richard B., Powell, Jason A., Thomas, Daniel, Guthridge, Mark A., Moore, Andrew, Ashman, Leonie K., Skelding, Kathryn A., Enjeti, Anoop, Verrills, Nicole M., Lee, Erwin M., Harrison, Celeste, Kahl, Richard, Flanagan, Hayley, Panicker, Nikita, Mashkani, Baratali, Don, Anthony S., Morris, Jonathan

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1

- Shahbazi, Jeyran, Scarlett, Christopher J., Lock, Richard B., Liu, Tao, Norris, Murray D., Liu, Bing, Haber, Michelle, Tee, Andrew E., Carrier, Alice, Biankin, Aandrew V., London, Wendy B., Marshall, Glenn M.

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia: an in vivo study

- Verrills, Nicole M., Liem, Natalia L., Liaw, Tracey Y. E., Hood, Brian D., Lock, Richard B., Kavallaris, Maria