Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells: LIFR Signalling in Leydig Cells
- Creator: Curley, Michael , Darbey, Annalucia , O'Donnell, Liza , Kilcoyne, Karen R. , Wilson, Kirsten , Mungall, Will , Rebourcet, Diane , Guo, Jingtao , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2022
Androgen receptor is dispensable for x-zone regression in the female adrenal but regulates post-partum corticosterone levels and protects cortex integrity
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, Ian J. , Jørgensen, Anne , Frederiksen, Hanne , Curley, Michael , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2021
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production
- Creator: Rebourcet, Diane , Mackay, Rosa , Darbey, Annalucia , Curley, Michael K. , Jørgensen, Anne , Frederiksen, Hanne , Mitchell, Rod T. , O'Shaughnessy, Peter J. , Nef, Serge , Smith, Lee B.
- Resource Type: journal article
- Date: 2020
Exogenous gonadotrophin stimulation induces partial maturation of human sertoli cells in a testicular xenotransplantation model for fertility preservation
- Creator: Hutka, Marsida , Smith, Lee B. , Goossens, Ellen , Wallace, W. Hamish B. , Stukenborg, Jan-Bernd , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Fertility preservation in childhood cancer: endocrine activity in prepubertal human testis xenografts exposed to a pubertal hormone environment
- Creator: Hutka, Marsida , Kadam, Prashant , Van Saen, Dorien , Homer, Natalie Z. M. , Onofre, Jaime , Wallace, W. Hamish B. , Smith, Lee B. , Stukenborg, Jan-Bernd , Goossens, Ellen , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Reconstitution of rat fetal testis during the masculinisation programming window induces focal dysgenesis consistent with testicular dysgenesis syndrome
- Creator: Smart, Ellie , Macdonald, Joni , Smith, Lee B. , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2020
Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mitchell, Rod T. , Smith, Lee B. , Mason, J. Ian , Rebourcet, Diane , Smith, Sarah , Traveres, Adriana , Alcaide-Corral, Carlos Jose , Frederiksen, Hanne , Jorgensen, Anne , Milne, Laura
- Resource Type: journal article
- Date: 2019
Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis
- Creator: O'Shaughnessy, Peter J. , Mitchell, Rod T. , Monteiro, Ana , O'Hara, Laura , Cruickshanks, Lyndsey , Claahsen-van der Grinten, Hedi , Brown, Pamela , Abel, Margaret , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing
- Creator: Gannon, Anne-Louise , O'Hara, Laura , Mason, J. Ian , Jørgensen, Anne , Frederiksen, Hanne , Milne, Laura , Smith, Sarah , Mitchell, Rod T. , Smith, Lee B.
- Resource Type: journal article
- Date: 2019
DMRT1 repression using a novel approach to genetic manipulation induces testicular dysgenesis in human fetal gonads
- Creator: Macdonald, Joni , Kilcoyne, Karen R. , Sharpe, Richard M. , Kavanagh, Áine , Anderson, Richard A. , Brown, Pamela , Smith, Lee B. , Jørgensen, Anne , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2018
Xenotransplantation as a model for human testicular development
- Creator: Hutka, Marsida , Smith, Lee B. , Mitchell, Rod T.
- Resource Type: journal article
- Date: 2017