A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered
- Creator: Jackson, Evangeline R. , Persson, Mika L. , Fish, Cameron J. , Findlay, Izac J. , Mueller, Sabine , Nazarian, Javad , Hulleman, Esther , van der Lugt, Jasper , Duchatel, Ryan J. , Dun, Matthew D.
- Resource Type: journal article
- Date: 2024
Diffuse midline glioma, H3K27-altered: illuminating the dark side of the moon
- Creator: Dun, Matthew D. , Odia, Yazmin , Arrillaga-Romany, Isabel
- Resource Type: journal article
- Date: 2024
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
- Creator: Duchatel, Ryan J. , Jackson, Evangeline R. , Kearney, Padraic S. , Jamaluddin, M. Fairuz B. , Douglas, Alicia M. , Beitaki, Tyrone , McEwen, Holly P. , Persson, Mika L. , Hocke, Emily A. , Jain, Vaibhav , Aksu, Michael , Manning, Elizabeth E. , Parackal, Sarah G. , Murray, Heather C. , Verrills, Nicole M. , Hua, Susan , Cairns, Murray J. , Alvaro, Frank , Dayas, Christopher V. , Dun, Matthew D. , Hua, S , de Bock, CE , Colino-Sanguino, Y , Kiltschewskij, Dylan , Valdes-Mora, F , Tsoli, M , Ziegler, DS , Cairns, MJ , Raabe, EH , Vitanza, NA , Hulleman, E , Phoenix, TN , Koschmann, C , Alvaro, F , Findlay, Izac J. , Dayas, CV , Tinkle, CL , Wheeler, H , Whittle, JR , Eisenstat, DD , Firestein, R , Mueller, S , Valvi, S , Hansford, JR , Ashley, DM , Mannan, Abdul , Gregory, SG , Kilburn, LB , Nazarian, J , Cain, JE , Dun, MD , Staudt, Dilana E. , Thomas, Bryce C. , Germon, Zacary P. , Laternser, Sandra
- Resource Type: journal article
- Date: 2024
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
- Creator: Venneti, Sriram , Kawakibi, Abed Rahman , Ramage, Samuel , Chi, Andrew , Wen, Patrick Y. , Arrillaga-Romany, Isabel , Batchelor, Tracy T. , Butowski, Nicholas A. , Sumrall, Ashley , Shonka, Nicole , Harrison, Rebecca A. , de Groot, John , Ji, Sunjong , Mehta, M , Hall, MD , Daghistani, D , Cloughesy, TF , Ellingson, BM , Beccaria, K , Varlet, P , Kim, MM , Umemura, Y , Garton, H , Waszak, Sebastian M. , Franson, A , Schwartz, J , Jain, R , Kachman, M , Baum, H , Burant, CF , Mottl, SL , Cartaxo, RT , John, V , Messinger, D , Sweha, StefanR , Qin, T , Peterson, E , Sajjakulnukit, P , Ravi, K , Waugh, A , Walling, D , Ding, Y , Xia, Z , Schwendeman, A , Hawes, D , Mota, Mateus , Yang, F , Judkins, AR , Wahl, D , Lyssiotis, CA , de la Nava, D , Alonso, MM , Eze, A , Spitzer, J , Schmidt, SV , Duchatel, Ryan J. , Pun, Matthew , Dun, Matthew D. , Cain, JE , Jiang, L , Stopka, SA , Baquer, G , Regan, MS , Filbin, MG , Agar, NYR , Zhao, L , Kumar-Sinha, C , Deogharkar, Akash , Mody, R , Chinnaiyan, A , Kurokawa, R , Pratt, D , Yadav, VN , Grill, J , Kline, C , Mueller, S , Resnick, A , Nazarian, J , Chung, Chan , Allen, JE , Odia, Y , Gardner, SL , Koschmann, C , Tarapore, Rohinton S.
- Resource Type: journal article
- Date: 2023
Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas
- Creator: Przystal, Justyna M. , Cosentino, Chiara Cianciolo , Biery, Matt C. , Myers, Carrie , Olson, James M. , Panditharatna, Eshini , Kritzer, Bettina , Mourabit, Sulayaman , Vitanza, Nicholas A. , Filbin, Mariella G. , de Iuliis, Geoffry N. , Dun, Matthew D. , Yadavilli, Sridevi , Koschmann, C , Cain, JE , Grotzer, MA , Waszak, SM , Mueller, S , Nazarian, J , Zhang, Jie , Laternser, Sandra , Bonner, Erin R. , Prasad, Rachna , Dawood, Adam A. , Lobeto, Nina , Chong, Wai Chin
- Resource Type: journal article
- Date: 2022
The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies
- Creator: Persson, Mika L. , Douglas, Alicia M. , Alvaro, Frank , Faridi, Pouya , Larsen, Martin R. , Alonso, Marta M. , Vitanza, Nicholas A. , Dun, Matthew D.
- Resource Type: journal article
- Date: 2022