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Garratt, Luke W., Sutanto, Erika N., Stick, Stephen M., Kicic, Anthony, Ling, Kak-Ming, Looi, Kevin, Iosifidis, Thomas, Martinovich, Kelly M., Shaw, Nicole C., Kicic-Starcevich, Elizabeth, Knight, Darryl A., Ranganathan, Sarath. European Respiratory Society; 2015. Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.
Waters, David W., Schuliga, Michael, Mutsaers, Steven E., Grainge, Christopher L., Knight, Darryl A., Pathinayake, Prabuddha S., Wei, Lan, Tan, Hui-Ying, Blokland, Kaj E. C., Jaffar, Jade, Westall, Glen P., Burgess, Janette K., Prele, Cecilia M.. MDPI AG; 2021. A senescence bystander effect in human lung fibroblasts.
Martinovich, Kelly M., Iosifidis, Thomas, Buckley, Alysia G., Looi, Kevin, Ling, Kak-Ming, Sutanto, Erika N., Kicic-Starcevich, Elizabeth, Garratt, Luke W., Shaw, Nicole C., Montgomery, Samuel, Lannigan, Fracis J., Knight, Darryl A., Kicic, Anthony, Stick, Stephen M.. Nature Publishing; 2017. Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics.
Prêle, Cecilia M., Miles, Tylah, Rinaldi, Catherine, Laurent, Geoffrey J., Knight, Darryl A., Fear, Mark, Hoyne, Gerard, McAnulty, Robin J., Mutsaers, Steven E., Pearce, David R., O'Donoghue, Robert J., Grainge, Chris, Barrett, Lucy, Birnie, Kimberly, Lucas, Andrew D., Baltic, Svetlana, Ernst, Matthias. European Respiratory Society; 2022. Plasma cell but not CD20-mediated B cell depletion protects from bleomycin-induced lung fibrosis..
Garratt, Luke W., Sutanto, Erika N., Knight, Darryl A., Stick, Stephen M., Kicic, Anthony, Ling, Kak-Ming, Looi, Kevin, Iosifidis, Thomas, Martinovich, Kelly M., Shaw, Nicole C., Buckley, Alysia G., Kicic-Starcevich, Elizabeth, Lannigan, Francis J.. American Thoracic Society; 2016. Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase.
Hsu, Alan Chen-Yu, Starkey, Malcolm R., Wark, Peter A., Hansbro, Philip M., Hanish, Irwan, Parsons, Kristy, Haw, Tatt Jhong, Howland, Linda J., Barr, Ian, Mahony, James B., Foster, Paul S., Knight, Darryl A.. American Thoracic Society; 2015. Targeting PI3K-p110α suppresses influenza virus infection in chronic obstructive pulmonary disease.
Kim, Richard Y., Pinkerton, James W., Hirota, Jeremy A., Wood, Lisa G., Simpson, Jodie L., Knight, Darryl A., Wark, Peter A., Gibson, Peter G., O'Neill, Luke A. J., Cooper, Matthew A., Horvat, Jay C., Hansbro, Philip M., Essilfie, Ama T., Robertson, Avril A. B., Baines, Katherine J., Brown, Alexandra C., Mayall, Jemma R., Ali, M. Khadem, Starkey, Malcolm R., Hansbro, Nicole G.. American Thoracic Society; 2017. Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma.
Murray, Lynne A., Dunmore, Rebecca, Camelo, Ana, Da Silva, Carla A., Gustavsson, Malin J., Habiel, David M., Hackett, Tillie L., Hogaboam, Cory M., Sleeman, Matthew A., Knight, Darryl A.. BioMed Central; 2017. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Liu, Gang, Cooley, Marion A., Tay, Hock, Foster, Paul S., Wark, Peter A., Horvat, Jay C., Bourke, Jane E., Grainge, Chris L., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Nair, Prema M., Hansbro, Philip M., Donovan, Chantal, Hsu, Alan C., Jarnicki, Andrew G., Haw, Tatt Jhong, Hansbro, Nicole G., Ge, Qi, Brown, Alexandra C.. John Wiley & Sons; 2017. Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c.
Liu, Gang, Cooley, Marion A., Jones, Berrnadette, Hansbro, Nicole G., Wark, Peter A., Horvat, Jay C., Argraves, W. Scott, Oliver, Brian G., Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M., Jarnicki, Andrew G., Borghuis, Theo, Nair, Prema M., Tjin, Gavin, Hsu, Alan C., Haw, Tatt Jhong, Fricker, Michael, Harrison, Celeste L.. American Society for Clinical Investigation; 2019. Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis.
Liu, Gang, Cooley, Marion A., Tjin, Gavin, Wark, Peter A. B., Walker, Marjorie M., Horvat, Jay C., Oliver, Brian G., Argraves, W. Scott, Knight, Darryl A., Burgess, Janette K., Hansbro, Philip M., Jarnicki, Andrew G., Hsu, Alan C-Y., Nair, Prema M., Haw, Tatt Jhong, FRICKER, Michael, Gellatly, Shaan L., Kim, Richard Y., Inman, Mark D.. American Society for Clinical Investigation; 2016. Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.
Looi, Kevin, Troy, Niamh M., Sutanto, Erika N., Zosky, Graeme R., Rigby, Paul J., Larcombe, Alexander N., Knight, Darryl A., Kicic, Anthony, Stick, Stephen M., Garratt, Luke W., Iosifidis, Thomas, Bosco, Anthony, Buckley, Alysia G., Ling, Kak-Ming, Martinovich, Kelly M., Kicic-Starcevich, Elizabeth, Shaw, Nicole C.. Taylor & Francis; 2016. Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.
Mahmood, Malik Quasir, Sohal, Sukhwinder Singh, Shukla, Shakti Dhar, Ward, Chris, Hardikar, Ashutosh, Noor, Wan Danial, Muller, Hans Konrad, Knight, Darryl A., Walters, Eugene Haydn. Dove Medical Press; 2015. Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction.
Moheimani, Fatemeh, Roth, Hollis M., Stick, Stephen M., Hansbro, Philip M., Hackett, Tillie-Louise, Knight, Darryl A., Cross, Jennifer, Reid, Andrew T., Shaheen, Furquan, Warner, Stephanie M., Hirota, Jeremy A., Kicic, Anthony, Hallstrand, Teal S., Kahn, Michael. Pergamon Press; 2015. Disruption of ß-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair.
Hirota, Jeremy A., Gold, Matthew J., McNagny, Kelly M., Knight, Darryl A., Hiebert, Paul R., Parkinson, Leigh G., Wee, Tracee, Smith, Dirk, Hansbro, Phil M., Carlsten, Chris, VanEeden, Stephen, Sin, Don D.. American Thoracic Society; 2015. The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 µm.
Christenson, Stephanie A., Brandsma, Corry-Anke, Campbell, Joshua D., Knight, Darryl A., Pechkovsky, Dmitri V., Hogg, James C., Timens, Wim, Postma, Dirkje S., Lenburg, Marc, Spira, Avrum. BioMed Central; 2013. miR-638 regulates gene expression networks associated with emphysematous lung destruction.
Blokland, Kaj E. C., Waters, David W., Burgess, Janette K., Knight, Darryl A., Schuliga, Michael, Read, Jane, Pouwels, Simon D., Grainge, Christopher L., Jaffar, Jade, Westall, Glen, Mutsaers, Steven E., Prele, Cecilia M.. MDPI AG; 2020. Senescence of IPF lung fibroblasts disrupt alveolar epithelial cell proliferation and promote migration in wound healing.
Waters, David W., Blokland, Kaj E. C., Pathinayake, Prabuddha S., Wei, Lan, Schuliga, Michael, Jaffar, Jade, Westall, Glen P., Hansbro, Philip M., Prele, Cecilia M., Mutsaers, Steven E., Bartlett, Nathan W., Burgess, Janette K., Grainge, Christopher L., Knight, Darryl A.. American Thoracic Society; 2019. STAT3 regulates the onset of oxidant-induced senescence in lung fibroblasts.
Ling, Kak-Ming, Sutanto, Erika N., Kicic, Anthony, Iosifidis, Thomas, Kicic-Starcevich, Elizabeth, Looi, Kevin, Garratt, Luke W., Martinovich, Kelly M., Lannigan, Francis J., Knight, Darryl A., Stick, Stephen M.. Wiley-Blackwell; 2016. Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma.
Habiel, David M., Camelo, Ana, Pilataxi, Fernanda, Clarke, Lori, Grant, Ethan, Lewis, Arthur, Moore, Bethany, Knight, Darryl A., Hogaboam, Cory M., Murray, Lynne A., Espindola, Milena, Burwell, Timothy, Hanna, Richard, Miranda, Elena, Carruthers, Alan, Bell, Matthew, Coelho, Ana Lucia, Liu, Hao. Nature Publishing Group; 2017. Divergent roles for clusterin in lung injury and repair.
Schuliga, Michael, Read, Jane, Blokland, Kaj E. C., Waters, David W., Burgess, Janette, Prele, Cecilia, Mutsaers, Steven E., Jaffar, Jade, Westall, Glen, Reid, Andrew, James, Allen, Grainge, Christopher, Knight, Darryl A.. Portland Press; 2020. Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner.
Williams, Teresa C., Loo, Su-Ling, Jackson, Crystal L., Alton, Kirby, Shimkets, Richard A., Girkin, Jason L., Bartlett, Nathan W., Nichol, Kristy S., Reid, Andrew T., Veerati, Punnam C., Esneau, Camille, Wark, Peter A. B., Grainge, Christopher L., Knight, Darryl A., Vincent, Thomas. Nature Publishing Group; 2022. IL-25 blockade augments antiviral immunity during respiratory virus infection.
Reid, Andrew T., Veerati, Punnam Chander, Knight, Darryl A., Gosens, Reinoud, Bartlett, Nathan W., Wark, Peter A., Grainge, Chris L., Stick, Stephen M., Kicic, Anthony, Moheimani, Fatemah, Hansbro, Philip M.. Elsevier; 2018. Persistent induction of goblet cell differentiation in the airways: therapeutic approaches.
Schuliga, Michael, Pechkovsky, Dmitri V., Mutsaers, Steven E., Jaffar, Jade, Westall, Glen, Grainge, Christopher, Knight, Darryl A., Read, Jane, Waters, David W., Blokland, Kaj E. C., Reid, Andrew T., Hogaboam, Cory M., Khalil, Nasreen, Burgess, Janette K., Prêle, Cecilia M.. Wiley-Blackwell; 2018. Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Fonceca, Angela M., Zosky, Graeme R., Bozanich, Elizabeth M., Sutanto, Erika N., Kicic, Anthony, McNamara, Paul S., Knight, Darryl A., Sly, Peter D., Turner, Debra J., Stick, Stephen M.. Biomed Central; 2018. Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung.
Shahangian, Kimia, Ngan, David A., Chen, H. H. Rachel, Oh, Yeni, Tam, Anthony, Wen, Jing, Cheung, Chung, Knight, Darryl A., Dorscheid, Delbert R., Hackett, Tillie L., Hughes, Michael R., McNagny, Kelly M., Hirota, Jeremy A., Niikura, Masahiro, Man, S. F. Paul, Sin, Don D.. BioMed Central (BMC); 2021. IL-4Ra blockade reduces influenza-associated morbidity in a murine model of allergic asthma.
Singanayagam, Aran, Glanville, Nicholas, Zhu, Jie, Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Grainge, Chris, Loo, Su-Ling, Veerati, Punnam Chander, Pathinayake, Prabuddha S., Nichol, Kristy S., Reid, Andrew T., James, Phillip L., Girkin, Jason L., Solari, Roberto, Wark, Peter A. B., Knight, Darryl A., Moffatt, Miriam F., Cookson, William O., Edwards, Michael R., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L., Ching, Yee Man, Marcellini, Andrea, Porter, James D., Toussaint, Marie, Walton, Ross P., Finney, Lydia J., Aniscenko, Julia. Nature Publishing Group; 2018. Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Hansbro, Philip M., Kim, Richard Y., Hirota, Jeremy A., Knight, Darryl A., Foster, Paul S., Horvat, Jay C., Starkey, Malcolm R., Donovan, Chantal, Dua, Kamal, Mayall, Jemma R., Liu, Gang, Hansbro, Nicole G., Simpson, Jodie L., Wood, Lisa G.. Wiley-Blackwell; 2017. Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.
Blokland, Kaj E. C., Habibie, Habibie, Borghuis, Theo, Teitsma, Greta J., Schuliga, Michael, Melgert, Barbro N., Knight, Darryl A., Brandsma, Corry-Anke, Pouwels, Simon D., Burgess, Janette K.. MDPI AG; 2021. Regulation of cellular senescence is independent from profibrotic fibroblast-deposited ECM.
Ghavami, Saeid, Yeganeh, Behzad, Dixon, Ian M. C., Unruh, Helmut, Knight, Darryl A., Post, Martin, Klonisch, Thomas, Halayko, Andrew J., Zeki, Amir A., Shojaei, Shahla, Kenyon, Nicholas J., Ott, Sean, Samali, Afshin, Patterson, John, Alizadeh, Javad, Moghadam, Adel Rezaei. American Physiological Society; 2018. Autophagy and the unfolded protein response promote profibrotic effects of TGF-β₁ in human lung fibroblasts.
Murray, Lynne A., Zhang, Huilan, Sleeman, Matthew A., Herzog, Erica L., Hogaboam, Cory M., Oak, Sameer R., Coelho, Ana Lucia, Herath, Athula, Flaherty, Kevin R., Lee, Joyce, Bell, Matt, Knight, Darryl A., Martinez, Fernando J.. American Thoracic Society; 2014. Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model.
Buckley, Alysia G., Looi, Kevin, Larcombe, Alexander N., Zosky, Graeme, Knight, Darryl A., Rigby, Paul J., Kicic, Anthony, Stick, Stephen M., Iosifidis, Thomas, Ling, Kak-Ming, Sutanto, Erika N., Martinovich, Kelly M., Kicic-Starcevich, Elizabeth, Garratt, Luke W., Shaw, Nicole C., Lannigan, Francis J.. Biomed Central (BMC); 2018. Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells.
Iosifidis, Thomas, Sutanto, Erika N., Kicic-Starcevich, Elizabeth, Vijayasekaran, Shyan, Lannigan, Francis J., Rigby, Paul J., Knight, Darryl A., Stick, Stephen M., Kicic, Anthony, Montgomery, Samuel T., Agudelo-Romero, Patricia, Looi, Kevin, Ling, Kak-Ming, Shaw, Nicole C., Garratt, Luke W., Hillas, Jessica, Martinovich, Kelly M.. MDPI AG; 2021. Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze.
Reid, Andrew .T, Nichol, Kristy S., Veerati, Punnam Chander, Moheimani, Fatemeh, Kicic, Anthony, Stick, Stephen M., Bartlett, Nathan W., Grainge, Chris L., Wark, Peter A. B., Hansbro, Philip M., Knight, Darryl A.. American Thoracic Society; 2020. Blocking notch3 signaling abolishes MUC5AC production in airway epithelial cells from individuals with asthma.
Murtha, Lucy A., Morten, Matthew, Boyle, Andrew J., Schuliga, Michael J., Mabotuwana, Nishani S., Hardy, Sean A., Waters, David W., Burgess, Janette K., Ngo, Doan T. M., Sverdlov, Aaron L., Knight, Darryl A.. Buck Institute for Age Research; 2019. The role of pathological aging in cardiac and pulmonary fibrosis.
Veerati, Punnam Chander, Reid, Andrew T., Nichol, Kristy S., Wark, Peter A. B., Knight, Darryl A., Bartlett, Nathan W., Grainge, Christopher L.. American Physiological Society; 2023. Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection.
Waters, David W., Blokland, Kaj E. C., Pathinayake, Prabuddha S., Burgess, Janette K., Mutsaers, Steven E., Prele, Cecilia M., Schuliga, Michael, Grainge, Christopher L., Knight, Darryl A.. American Physiological Society; 2018. Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis.
Iosifidis, Thomas, Sutanto, Erika N., Martinovich, Kelly M., Shaw, Nicole C., Montgomery, Samuel T., Kicic-Starcevich, Elizabeth, Karpievitch, Yuliya V., Le Souëf, Peter, Laing, Ingrid A., Vijayasekaran, Shyan, Lannigan, Francis J., Rigby, Paul J., Buckley, Alysia G., Hancock, Robert E. W., Knight, Darryl A., Stick, Stephen M., Kicic, Anthony, Coleman, Laura, Gill, Erin E., Lee, Amy H., Ling, Kak-Ming, Hillas, Jessica, Looi, Kevin, Garratt, Luke W.. American Society for Clinical Investigation; 2020. Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze.
Veerati, Punnam Chander, Troy, Niamh Mary, Reid, Andrew T., Li, Ngan Fung, Nichol, Kristy S., Kaur, Parwinder, Maltby, Steven, Wark, Peter A. B., Knight, Darryl A., Bosco, Anthony, Grainge, Chris L., Bartlett, Nathan W.. Frontiers Research Foundation; 2020. Airway epithelial cell immunity is delayed during rhinovirus infection in asthma and COPD.
Blokland, Kaj E. C., Nizamoglu, Mehmet, Habibie, Habibie, Borghuis, Theo, Schuliga, Michael, Melgert, Barbro N., Knight, Darryl A., Brandsma, Corry-Anke, Pouwels, Simon D., Burgess, Janette K.. Frontiers Research Foundation; 2022. Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts.
Read, Jane, Reid, Andrew T., Schuliga, Michael, Thomson, Claire, Plit, Marshall, Mejia, Ross, Knight, Darryl A., Lize, Muriel, Kasmi, Karim E., Grainge, Christopher, Stahl, Heiko. Portland Press Ltd; 2024. Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury.
Schuliga, Michael, Kanwal, Amama, Read, Jane, Blokland, Kaj E. C., Burgess, Janette K., Prele, Cecilia M., Mutsaers, Steven E., Grainge, Christopher, Thomson, Claire, James, Allen, Bartlett, Nathan W., Knight, Darryl A.. American Physiological Society; 2021. A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF.
Tu, Xiaofan, Kim, Richard Y., Loering, Svenja, Nguyen, Duc H., Nair, Prema Mono, Haw, Tatt Jhong, Alemao, Charlotte A., Faiz, Alen, Tay, Hock L., Wark, Peter A. B., Knight, Darryl A., Foster, Paul S., Brown, Alexandra C., Bosco, Anthony, Horvat, Jay C., Hansbro, Philip M., Donovan, Chantal, de Jong, Emma, Jones-Freeman, Bernadette, Ali, Md Khadem, Gomez, Henry M., Budden, Kurtis F., Starkey, Malcolm R., Cameron, Guy J. M.. Elsevier; 2022. Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap.
Veerati, Punnam Chander, Nichol, Kristy S., Read, Jane M., Bartlett, Nathan W., Wark, Peter A. B., Knight, Darryl A., Grainge, Christopher L., Reid, Andrew T.. American Physiological Society; 2022. Conditionally reprogrammed asthmatic bronchial epithelial cells express lower FOXJ1 at terminal differentiation and lower IFNs following RV-A1 infection.