https://novaprd-lb.newcastle.edu.au/vital/access/manager/Index en-au 5 Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:13258 Sat 24 Mar 2018 08:15:59 AEDT ]]> Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study Cohort https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:28445 −2 at rs685352 to 6.4x10−4 at rs560764, whereas association could not be confirmed for SNPs at the 15q25 locus, with P values ranging from 8.0x10−1 to 6.4x10−1. Ocular biometric analysis revealed that axial length was the most likely trait underlying the refractive error association at the 15q14 locus for SNPs rs560766 (P =0.0054), rs634990 (P =0.0086), and rs8032019 (P =0.0081). Conclusions: Our results confirm the association with refractive error at the 15q14 locus but do not support the association observed at the 15q25 locus. Axial length seemed to be a major parameter at the 15q14 locus, underscoring the importance of this locus in myopia and future clinical treatment. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.]]> Sat 24 Mar 2018 07:29:01 AEDT ]]>