https://novaprd-lb.newcastle.edu.au/vital/access/manager/Index en-au 5 Quality of acute care and long-term quality of life and survival: the Australian Stroke Clinical Registry https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:34583 Wed 23 Feb 2022 16:04:47 AEDT ]]> Ultra-Long Transfers for Endovascular Thrombectomy - Mission Impossible?: The Australia-New Zealand Experience https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:50318 300 miles would benefit from EVT, achieving rates of functional independence (modified Rankin Scale [mRS] score of 0-2) at 3 months similar to those patients treated at the comprehensive stroke center in the randomized EVT extended window trials and that the selection of patients with computed tomography perfusion (CTP) at the referring site would be associated with ordinal shift toward better outcomes on the mRS. Methods: This is a retrospective analysis of patients transferred from 31 referring hospitals >300 miles (measured by the most direct road distance) to 9 comprehensive stroke centers in Australia and New Zealand for EVT consideration (April 2016 through May 2021). Results: There were 131 patients; the median age was 64 [53-74] years and the median baseline National Institutes of Health Stroke Scale score was 16 [12-22]. At baseline, 79 patients (60.3%) had noncontrast CT+CT angiography, 52 (39.7%) also had CTP. At the comprehensive stroke center, 114 (87%) patients underwent cerebral angiography, and 96 (73.3%) proceeded to EVT. At 3 months, 62 patients (48.4%) had an mRS score of 0 to 2 and 81 (63.3%) mRS score of 0 to 3. CTP selection at the referring site was not associated with better ordinal scores on the mRS at 3 months (mRS median of 2 [1-3] versus 3 [1-6] in the patients selected with noncontrast CT+CT angiography, P=0.1). Nevertheless, patients selected with CTP were less likely to have an mRS score of 5 to 6 (odds ratio 0.03 [0.01-0.19]; P<0.01). Conclusions: In selected patients transferred >300 miles, there was a benefit for EVT, with outcomes similar to those treated in the comprehensive stroke center in the EVT extended window trials. Remote hospital CTP selection was not associated with ordinal mRS improvement, but was associated with fewer very poor 3-month outcomes.]]> Tue 18 Jul 2023 14:30:07 AEST ]]> HIV infection is influenced by dynamin at 3 independent points in the viral life cycle https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:31291 Thu 13 Jan 2022 10:28:35 AEDT ]]> STroke imAging pRevention and treatment (START): a longitudinal stroke cohort study: clinical trials protocol https://novaprd-lb.newcastle.edu.au/vital/access/manager/Repository/uon:23444 Sat 24 Mar 2018 07:13:32 AEDT ]]>